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Organic Letters, 2006
[reaction: see text] A simple method for the direct ortho-arylation of benzoic acid amides has been developed. The palladium-catalyzed reactions proceed in trifluoroacetic acid and require the presence of stoichiometric silver acetate. This presents an alternative to the currently used ortho-lithiation strategies for the synthesis of arylated benzoic ...
Dmitry, Shabashov, Olafs, Daugulis
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[reaction: see text] A simple method for the direct ortho-arylation of benzoic acid amides has been developed. The palladium-catalyzed reactions proceed in trifluoroacetic acid and require the presence of stoichiometric silver acetate. This presents an alternative to the currently used ortho-lithiation strategies for the synthesis of arylated benzoic ...
Dmitry, Shabashov, Olafs, Daugulis
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Intercalation of Benzamide into Kaolinite
Journal of Colloid and Interface Science, 2000Well-crystallized kaolinite (K) was initially reacted at 60 degrees C with a water/dimethylsulfoxide (DMSO) mixture and the resulting intercalation derivative (K-DMSO) was characterized by powder X-ray diffractometry (PXRD), thermal analysis (simultaneous TG and DSC), and Fourier-transformed infrared spectroscopy (FTIR).
, Gardolinski +3 more
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Chemical Synthesis of Benzamide Riboside
Current Medicinal Chemistry, 2002The C-glycosidic nicotinamide riboside analogue (1) was prepared by reaction of ribonolactone 16 with the lithiated 2-oxazoline 13 followed by triethylsilane reduction of the hemiacetal 17 to the tetrahydrofurane 18. Cleavage of the oxazoline group in 20 to the acid 21, conversion of the acid chloride 22 to the amide 23, and hydrogenative debenzylation
K, Krohn, H, Dörner, M, Zukowski
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Alkylating benzamides with melanoma cytotoxicity
Melanoma Research, 2004Radioiodinated N-(2-(diethylamino)ethyl)benzamides have recently been discovered as selective agents for melanotic melanoma and are used for scintigraphic imaging in nuclear medicine. Owing to the high binding capacity, benzamide derivatives conjugated with alkylating cytostatics were synthesized and tested for their potential for targeted drug ...
Markus, Wolf +6 more
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L'Encephale, 1976
The comparison of the therapeutic effects of three molecules belonging to the substituted benzamide family allows the following observations: --the three products are generally well tolerated by the organism; --at sufficient doses they act as a major tranquilizers: -sulpiride is chiefly a disinhibitor but also has antipsychotic properties; -sultopride ...
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The comparison of the therapeutic effects of three molecules belonging to the substituted benzamide family allows the following observations: --the three products are generally well tolerated by the organism; --at sufficient doses they act as a major tranquilizers: -sulpiride is chiefly a disinhibitor but also has antipsychotic properties; -sultopride ...
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Benzamide (Metoclopramid, Alizaprid)
1992Metoclopramid ist aufgrund seiner nachgewiesenen Wirksamkeit bei den verschiedenen Chemotherapien und der abschatzbaren unerwunschten Wirkungen die Referenzsubstanz zur Behandlung des zytostatika-induzierten Erbrechens (1, 18, 20, 23, 25, 26, 29–36, 41, 51, 56, 58, 61–66, 69, 71, 73, 75). Allerdings mus der ubliche (konventionelle) Niedrigdosisbereich (
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