Results 21 to 30 of about 33,916 (231)

A structural systematic study of four isomers of difluoro-N-(3-pyridyl)benzamide [PDF]

, 2009
The four isomers 2,4-, (I), 2,5-, (II), 3,4-, (III), and 3,5-difluoro-N-(3-pyridyl)benzamide, (IV), all with formula C12H8F2N2O, display molecular similarity, with interplanar angles between the C6/C5N rings ranging from 2.94 (11)° in (IV) to 4.48 (18 ...
Anderson, Frankie P., Gallagher, John F., Lough, Alan J., McMahon, Joyce   +3 more
core   +1 more source

2-(Methylsulfinyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the crystal of the title compound, C(8)H(9)NO(2)S, synthesized by the oxidation of 2-(methyl-sulfan-yl)benzamide using NaOCl with 2,2,6,6-tetra-methyl-piperidyl-1-oxy (TEMPO) as the catalyst, mol-ecules are linked via inter-molecular N-H⋯O(amide) hydrogen bonds, forming centrosymmetric amide-amide dimers which are extended into a two-dimensional ...
openaire   +3 more sources

N-(2-Nitrophenyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the title compound, C(13)H(10)N(2)O(3), the central C-C(=O)-N-C amide unit makes dihedral angles of 21.68 (4) and 19.08 (4)°, respectively, with the phenyl and nitro-benzene rings. The two aromatic rings are inclined at 3.74 (3)° and the nitro group is skewed out of the attached benzene ring plane by 18.55 (8)°. An intra-molecular N-H⋯O inter-action
Aamer Saeed, Jim Simpson
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4-Methyl-N-[2-(pyridin-2-yl)ethylcarbamothioyl]benzamide

Acta Crystallographica Section E, 2014
In the title compound, C16H17N3OS, the dihedral angle between the planes of the benzene and pyridine rings is 71.33 (15)°. An intramolecular N—H...O hydrogen bond is present.
Farook Adam, Nadiah Ameram, Naser Eltaher Eltayeb   +2 more
doaj   +1 more source

Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis [PDF]

, 2013
PMCID ...
A Compston, A Shetty, A Zimmer, AC Howlett, AE Bygrave, C Bolton, C Delarasse, C Delarasse, C Teuscher, Carolyn Tanner, CS Wu, CS Wu, D Baker, D Baker, D Baker, D Baker, D Baker, D Baker, D Baker, D McHugh, David Baker, David L. Selwood, DL Smith-Bouvier, E de Lago, E Kozela, E Montero, E Zurita, F Docagne, F Wu, G Disanto, G Musumeci, G Paltser, G Pryce, G Pryce, G Wotherspoon, Gareth Pryce, Gavin Giovannoni, Gregory J. Michael, H Kataoka, HM Vesterinen, I Mendel, J Corey-Bloom, J Karlsson, J Palazuelos, JA Encinas, JB Davis, JH Slingsby, JK O'Neill, JL Croxford, JL Croxford, JM Coquet, JP Zajicek, K Li, K Maresz, KM Spach, L Cristino, LM Olsson, LS Whyte, M Sundvall, M Webb, MF Festing, NA Balenga, NE Buckley, O Ofek, PC Staton, PD Fillmore, PM Hoi, RA Ross, RA Ross, RC Axtell, RG Pertwee, RG Pertwee, RJ Butterfield, Roberto Furlan, RS Graves, Ruth A. Ross, S Al-Izki, S Al-Izki, S Amor, S Amor, S Amor, S Katona, S Levine, S Levine, S Rossi, S Saadoun, Samuel J. Jackson, SC Landis, SJ Allen, Sofia Sisay, V Devonshire, Y Okuda, ZY Lou   +92 more
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N-(3,4-Dimethylphenyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2007
The conformation of the NH bond in the structure of the title compound (N34DMPBA), C(15)H(15)NO, is anti to the meta-methyl substituent in the aniline ring, similar to that observed with respect to the meta-chloro substituent in N-(3,4-dichloro-phen-yl)benzamide (N34DCPBA), but in contrast to the syn conformation observed with respect to the meta ...
B. Thimme Gowda, Miroslav Tokarčík, Jozef Kožíšek, B. P. Sowmya, Hartmut Fuess   +4 more
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Crystal structure of 4-methyl-N-{[1-(4-methylbenzoyl)piperidin-4-yl]methyl}benzamide

Acta Crystallographica Section E, 2014
In the title compound, C22H27N2O2, the piperidine ring adopts a half-chair conformation with the benzene rings inclined in a trans orientation with respect to the piperidine ring [dihedral angle between the benzene rings = 89.1 (1)°].
K. Prathebha, D. Reuben Jonathan, S. Sathya, R. Vasanthi, G. Usha   +4 more
doaj   +1 more source

Discovery of Indole-Containing Benzamide Derivatives as HDAC1 Inhibitors with In Vitro and In Vivo Antitumor Activities

Pharmaceutical Fronts, 2022
Targeting histone deacetylases (HDACs) has become an important focus in cancer inhibition. The pharmacophore of HDAC inhibitors (HDACis) reported so far is composed of three parts: a zinc-binding group (ZBG), a hydrophobic cavity-binding linker, and a ...
Xiu Gu, Xin-Yan Peng, Hao Zhang, Bo Han, Min-Ru Jiao, Qiu-Shi Chen, Qing-Wei Zhang   +6 more
doaj   +1 more source

N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide

Molbank, 2019
The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by various spectroscopic methods (
Hamad H. Al Mamari, Nasser Al Awaimri, Yousuf Al Lawati   +2 more
doaj   +1 more source

One molecule, three crystal structures: conformational trimorphism of N-[(1S)-1-phenylethyl]benzamide

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C15H15NO, is an enantiopure small molecule, which has been synthesized many times, although its crystal structure was never determined. By recrystallization from a variety of solvent mixtures (pure acetonitrile, ethanol–water, toluene–
Fermin Flores Manuel, Martha Sosa Rivadeneyra, Sylvain Bernès   +2 more
doaj   +1 more source