Results 31 to 40 of about 16,778 (193)

The 68Ga-labeled chlorinated benzamide derivative: A novel PET imaging probe for detection of melanoma

Results in Chemistry
The benzamide structure is known for its ability to target melanin, a specific biomarker of melanoma. Therefore, we developed a new chlorinated benzamide structure for the detection of melanoma on positron emission tomography (PET). The derived benzamide
Yejin Seo, Dagyeong Hong, Eunsu Kim, Chaewon Lee, Boreum Song, Wookyeong Jeong, Jiyu Kim, Seong-Young Kwon, Dong-Yeon Kim, Ayoung Pyo   +9 more
doaj   +1 more source

Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides

Beilstein Journal of Organic Chemistry, 2017
Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination.
Ryota Miyaji, Yuuki Wada, Akira Matsumoto, Keisuke Asano, Seijiro Matsubara   +4 more
doaj   +1 more source

Studies of the Synthesis of Fused Isoxazoline/Isoquinolinones and Evaluation of the Antifungal Activity of Isoxazole-like Benzamide and Isoquinolinone Hybrids

Molecules
Isoxazole derivatives (isoxazoles, isoxazolines, and isoxazolidines) are present in the structure of several natural products and/or pharmaceutically interesting compounds.
Konstantinos A. Ouzounthanasis, Jasmina Glamočlija, Ana Ćirić, Alexandros E. Koumbis   +3 more
doaj   +1 more source

Crystal structure of 4-chloro-N-[2-(piperidin-1-yl)ethyl]benzamide monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C14H19ClN2O2·H2O, the piperdine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and that of the phenyl ring is 41.64 (1)°.
K. Prathebha, D. Reuben Jonathan, B. K Revathi, S. Sathya, G. Usha   +4 more
doaj   +1 more source

A Strong Lewis Acidic Diethylsilylium Catalyst for Direct Sulfonamidation of Challenging Ketones

Advanced Science, EarlyView.
Low‐substitution‐order silylium ions (R2HSi+) exhibit exceptional Lewis acidic activity. We report diethylsilylium‐catalyzed reductive sulfonamidation of functionalized ketones to access β‐amino esters. The in situ generated ion pair shows enhanced reactivity, with diethylsilane serving as both reductant and precatalyst. The developed protocol proceeds
Woo Hee Kim, Muhammad Israr, You Kyoung Chung, Shinwon Ham, Joonsuk Huh, Han Yong Bae   +5 more
wiley   +1 more source

Crystal structure of 4-methoxy-N-[(pyrrolidin-1-yl)carbothioyl]benzamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C13H16N2O2S, the pyrrolidine ring has a twisted conformation on the central –CH2–CH2– bond. Its mean plane is inclined to the 4-methoxybenzoyl ring by 72.79 (15)°.
Khairi Suhud, Lee Yook Heng, Siti Aishah Hasbullah, Musa Ahmad, Mohammad B. Kassim   +4 more
doaj   +1 more source

Crystal structures and hydrogen-bonding analysis of a series of benzamide complexes of zinc(II) chloride

Acta Crystallographica Section E: Crystallographic Communications, 2021
Ionic co-crystals are co-crystals between organic molecules and inorganic salt coformers. Co-crystals of pharmaceuticals are of interest to help control polymorph formation and potentially improve stability and other physical properties.
Elizabeth Tinapple, Sam Farrar, Dean H. Johnston   +2 more
doaj   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

N,N′-(Ethane-1,2-diyl)bis(2-chlorobenzamide)

IUCrData, 2016
The title compound, C16H14Cl2N2O2, crystallized with one half-molecule in the asymmetric unit; the whole molecule is generated by inversion symmetry, the center of inversion being situated at the middle of the bridging –CH2—CH2– bond.
U. Mohamooda Sumaya, D. Reuben Jonathan, E. R. A. Dravida Thendral, B. K. Revathi, G. Usha   +4 more
doaj   +1 more source

Crystal structure of 2-(1,3,7,9-tetramethyl-2,4,6,8-tetraoxo-1,2,3,4,6,7,8,9-octahydropyrido[2,3-d:6,5-d′]dipyrimidin-5-yl)benzamide dimethylformamide hemisolvate

Acta Crystallographica Section E, 2014
The title compound, C20H18N6O5·0.5C3H7NO, crystallized as a dimethylformamide (DMF) solvate. In the main molecule, the dihedral angle between the pyridodipyrimidine fused-ring system and the benzamide substituent is 82.26 (11)°.
Armen Ayvazyan
doaj   +1 more source