Results 51 to 60 of about 33,916 (231)

Structure, function and inhibition of poly(ADP-ribose)polymerase, member 14 (PARP14) [PDF]

, 2018
Poly(ADP-ribose)polymerase, member 14 (PARP14, alternatively named ARTD8, BAL2, and COAST6) is an intracellular mono(ADP-ribosyl) transferase. PARP14 transfers a negatively charged ADP-ribose unit from a donor NAD+ molecule onto a target protein, post ...
Levonis, Stephan M, Schweiker, Stephanie S, Sherry, Madeleine, Tauber, Amanda   +3 more
core   +1 more source

Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors

Metabolites, 2018
A series of benzamides incorporating 4-sulfamoyl moieties were obtained by reacting 4-sulfamoyl benzoic acid with primary and secondary amines and amino acids. These sulfonamides were investigated as inhibitors of the metalloenzyme carbonic anhydrase (CA,
Morteza Abdoli, Murat Bozdag, Andrea Angeli, Claudiu T. Supuran   +3 more
doaj   +1 more source

Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]

, 2017
Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Chiriță, Cornel, Marineci, Cristina D., Negreș, Simona, Nuță, Diana C., Ștefănescu, Emil   +4 more
core   +4 more sources

Crystal structure and Hirshfeld surface analysis of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-N-(pyridin-2-ylmethyl)benzamide

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H18F2N2O3, crystallizes with two independent molecules (A and B) in the asymmetric unit. They differ essentially in the orientation of the pyridine ring with respect to the benzene ring; these two rings are inclined to each other ...
G. Artheswari, V. Maheshwaran, N. Gautham   +2 more
doaj   +1 more source

Crystal structures and hydrogen-bonding analysis of a series of benzamide complexes of zinc(II) chloride

Acta Crystallographica Section E: Crystallographic Communications, 2021
Ionic co-crystals are co-crystals between organic molecules and inorganic salt coformers. Co-crystals of pharmaceuticals are of interest to help control polymorph formation and potentially improve stability and other physical properties.
Elizabeth Tinapple, Sam Farrar, Dean H. Johnston   +2 more
doaj   +1 more source

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]

, 2014
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C., Arbes S. J., Asokananthan N., Billson J., Boyd M. J., Brown A., Brown A. D., Chan W. C., Chen J. C., Clive Robinson, Comoy E. E., David R. Garrod, Fattouh R., Gary K. Newton, Gelber L. E., Gough L., Jahnsen F. L., Jie Chen, Jihui Zhang, Jonathan P. Richardson, Kerry Jenkins, King C., Liu H., Marcaccini S., Mark R. Stewart, Meriel R. Major, Milan D. S., Moffatt M. F., Möller G. M., Nicola J. Francis-Newton, Peat J. K., Peat J. K., Pei Lai, Pichavant M., Platts-Mills T. A., Platts-Mills T. A., Platts-Mills T. A. E., Platts-Mills T. A. E., Prefontaine D., Purello-D’Ambrosia F., Rebekah E. Key, Robinson C., Silvestri M., Smith J. M., Sporik R., Squillace S. P., Steven M. Lloyd, Stewart G. A., Stuart Firth-Clark, Takai T., Trevor R. Perrior, Wan H., Ying S., Zhang J., Zhang J., Zhang J., Zhang J.   +56 more
core   +2 more sources

N-(Pyrrolidin-1-ylcarbothioyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title compound, C(12)H(14)N(2)OS, the pyrrolidine ring adopts an envelope conformation with the C atom at the 3-position as the flap and makes a dihedral angle of 65.80 (9)° with the benzene ring. In the crystal, N-H⋯O hydrogen bonds join c-glide related mol-ecules into chains extended along [001] that are further connected into (100) layers via
Al-Abbasi, Aisha A., Mohamed Tahir, Mohamed Ibrahim, Kassim, Mohammad   +2 more
openaire   +3 more sources

Nickel-catalyzed transamidation of aliphatic amide derivatives. [PDF]

, 2017
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained ...
Baker, Emma L, Dander, Jacob E, Garg, Neil K   +2 more
core   +1 more source

N-(4-Cyanobenzyl)benzamide

Acta Crystallographica Section E Structure Reports Online, 2008
The title compound, C(15)H(12)N(2)O, is a derivative of 4-(amino-meth-yl)benzonitrile, an important pestcide inter-mediate. In the crystal structure, mol-ecules are linked via inter-molecular N-H⋯O hydrogen bonds, forming infinite chains.
Hong-Jun Zhu, Wei Chen, Hai-Jun Ma, Li-Qin Guo, Yi-Li Tong   +4 more
openaire   +3 more sources

The 68Ga-labeled chlorinated benzamide derivative: A novel PET imaging probe for detection of melanoma

Results in Chemistry
The benzamide structure is known for its ability to target melanin, a specific biomarker of melanoma. Therefore, we developed a new chlorinated benzamide structure for the detection of melanoma on positron emission tomography (PET). The derived benzamide
Yejin Seo, Dagyeong Hong, Eunsu Kim, Chaewon Lee, Boreum Song, Wookyeong Jeong, Jiyu Kim, Seong-Young Kwon, Dong-Yeon Kim, Ayoung Pyo   +9 more
doaj   +1 more source