Results 131 to 140 of about 24,787 (257)

Design, Synthesis and molecular docking study of hybrids of quinazolin-4(3H)-one as anticancer agents

Ars Pharmaceutica
A series of 4-(2-(4-substituted phenyl)-4-oxoquinazolin-3(4H)-yl)-N-(2-(4-fluorophenyl)-4-oxo-5-(arylidene)thiazolidin-3-yl) benzamides (VIa-n) have been synthesized by condensation of N-(2-(4-fluorophenyl)-4-oxothiazolidin-3-yl)-4-(4-oxo-2-(4 ...
Sukanya Nara, Achaiah Garlapati
doaj   +1 more source

Substituted Benzamides Containing Azaspiro Rings as Upregulators of Apolipoprotein A-I Transcription

Molecules, 2012
Apolipoprotein A-I (Apo A-I) is the principal protein component of high density lipoprotein (HDL), which is generally considered as a potential therapeutic target against atherosclerosis.
Bin Hong, Xiao-Jian Jia, Xiao-Fang Chen, Shu-Yi Si, Li Wang, Wei Jiang, Yuan Yang, Yu Du   +7 more
doaj   +1 more source

Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors [PDF]

, 2014
Fragments based on the VEGFR2i Semaxanib (SU5416, (vascular endothelial growth factor receptor-2 inhibitor) and the HDACi (histone deacetylase inhibitor) SAHA (suberanilohydroxamic acid) have been merged to form a range of low molecular weight dual ...
Bradner, James E, Chuckowree, Irina, Coxhead, Peter, Guille, Matthew, Librizzi, Mariangela, Paranal, Ronald M, Patel, Hiren, Spencer, John, Wang, Minghua, Williams, Robin S B, Zuckermann, Alexandra   +10 more
core   +1 more source

Crystal structure and Hirshfeld surface analysis of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-N-(pyridin-2-ylmethyl)benzamide [PDF]

, 2019
G. Artheswari, V. Maheshwaran, N. Gautham   +2 more
openalex   +1 more source

In silico identification of benzamide-based aryl halides as EGFR inhibitors: multi-ligand ADMET, pharmacophore mapping, and target prediction

In Silico Research in Biomedicine
Cancer is one of the greatest global health challenges, with specific costs of US$25 trillion by 2050, including treatment and socioeconomic impacts. The epidermal growth factor receptor (EGFR), a central tyrosine kinase, is a key target for anticancer ...
Caroline do Nascimento Gonçalves, Matheus Nunes da Rocha, Emmanuel Silva Marinho   +2 more
doaj   +1 more source

Anticoccidial therapy small guide [PDF]

Medicamentul Veterinar, 2007
Being a major challenge, because of ingenious parasite's survival strategies and treatment's transience, anticoccidal therapy it is a major priority. In this respect, therapeutic conduct must be adjusted as well is possible on the most efficient drug ...
Cristina, T. Romeo
doaj  

2-(Difluoroboryloxy)benzamide

Molbank
The title compound has been fully characterised by NMR for the first time. Fully assigned 1H and 13C NMR spectra, and the X-ray structure of two different polymorphs are presented. The polymorphs show similar molecular geometries but exhibit significantly different patterns of intermolecular interactions.
R. Alan Aitken, Hibet E. M. Akkache, David B. Cordes, Aidan P. McKay, Dorian Moreau   +4 more
openaire   +2 more sources

Palladium‐Catalyzed C−H Iodination of N‐(8‐Quinolinyl)benzamide Derivatives Under Electrochemical and Non‐Electrochemical Conditions [PDF]

, 2018
Katsuya Sano, Naoki Kimura, Takuya Kochi, Fumitoshi Kakiuchi   +3 more
openalex   +1 more source

How Does the Benzamide Antipsychotic Amisulpride get into the Brain?—An In Vitro Approach Comparing Amisulpride with Clozapine [PDF]

, 2003
Sebastian Härtter, Sabine Hüwel, Tina Lohmann, Amal Abou el ela, Peter Langguth, Christoph Hiemke, Hans‐Joachim Galla   +6 more
openalex   +1 more source

An unusual endo-selective C-H hydroarylationof norbornene by the Rh(I)-catalyzed reactionof benzamides

Nature Communications, 2017
Investigating unusual organometallic pathways may help to efficiently control product selectivity in homogeneous catalysis. Here, the authors report the hydroarylation of aromatic amides with norbornene derivatives and propose the formation of a rhodium ...
Kaname Shibata, Satoko Natsui, Mamoru Tobisu, Yoshiya Fukumoto, Naoto Chatani   +4 more
doaj   +1 more source