Results 91 to 100 of about 8,103 (214)

N-Cyclohexyl-N-(prop-2-en-1-yl)benzenesulfonamide

, 2009
The title compound, C15H21NO2S, synthesized by N-alkylation of cyclohexylamine benzenesulfonamide with allyl iodide, is of interest as a precursor to biologically active sulfur-containing heterocyclic compounds.
Islam Ullah Khan, Muhammad Zia-ur-Rehman, Zeeshan Haider, Muhammad Nadeem Arshad, Muhammad Shafiq   +4 more
core   +1 more source

3,5-Dichloro-N-(2,4-dichlorophenyl)benzenesulfonamide [PDF]

IUCrData, 2017
The molecule of the title compound, C12H7Cl4NO2S, is U-shaped, with the central C—S—N—C segment having a torsion angle of −58.7 (3)°. The dihedral angle between the benzene rings is 40.23 (2)°. Further, the ortho Cl atom on the aniline ring is syn to the N—H bond in the central –C—S(O2)—NH—C– segment.
K. Shakuntala, N. K. Lokanath, S. Naveen, P. A. Suchetan   +3 more
openaire   +3 more sources

Novel Application of UHPLC–MS, HRMS, and 2D‐NMR for Structural Elucidation of Eletriptan Hydrobromide and Its Novel Degradation Products

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT A stability‐indicating UHPLC–MS method was developed to investigate the stress degradation behavior of eletriptan hydrobromide under ICH‐recommended acidic, alkaline, neutral, oxidative, thermal, and photolytic conditions. Significant degradation was observed only under acidic and oxidative stress.
Dastagiri Reddy Bhuma, Venkata Kanaka Srivani Maddala, Suresh Salakolasu, Naresh Kumar Katari   +3 more
wiley   +1 more source

The crystal structures determination and Hirshfeld surface analysis of N-(4-bromo-3-methoxyphenyl)- and N-{[3-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]methyl}- derivatives of N-{[3-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]methyl}benzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications
Two new phenylsulfonylindole derivatives, namely, N-{[3-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]methyl}-N-(4-bromo-3-methoxyphenyl)benzenesulfonamide, C28H22Br2N2O5S2, (I), and N,N-bis{[3-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]methyl}benzenesulfonamide ...
S. Madhan, M. NizamMohideen, Vinayagam Pavunkumar, Arasambattu K. MohanaKrishnan   +3 more
doaj   +1 more source

4-Amino-N-(2-hydroxy-4-pentadecylbenzylidene)benzenesulfonamide

, 2011
4-Amino-N-(2-hydroxy-4-pentadecylbenzylidene)benzenesulfonamide has been synthesized by reaction of 2-hydroxy-4-pentadecylbenzaldehyde with 4-aminobenzenesulfonamide in the presence of acetic acid in ethanol.
Amorn Petsom, Gadada Naganagowda
core   +1 more source

New Quinoline Kinase Inhibitors With Good Selectivity for NAK Kinases and Anti‐Tumor Activity Against Ewing Sarcoma

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Focusing on the discovery of new therapeutics for childhood cancer, novel quinoline derivatives were synthesized and demonstrated activity against Ewing sarcoma. A target search was performed against a panel of kinases, and the compounds showed selectivity for the NAK family, mainly GAK, which was confirmed by enzyme kinetic assays.
Caroline de Bem Gentz, Thais Helena Maciel Fernandes, Marcela Silva Lopes, Lewis Elson, Andreas Krämer, Lucas Rodrigo de Souza, Isadora Serraglio Fortes, Geórgia Silva Pinto, Martha Cestari Silva Martins, Henrique Barros de Lima, André da Silva Santiago, Lauro José Gregianin, Katlin Brauer Massirer, Mário Henrique Bengtson, Rafael Roesler, Stefan Knapp, Stefan A. Laufer, Saulo Fernandes de Andrade   +17 more
wiley   +1 more source

Yield, physical state, melting point, purity, and spectroscopic data (GS-MS, IR, ¹H-NMR) of N-(4-acetylphenyl)benzenesulfonamide (1) and N-{4-[(E)-3-(4-nitrophenyl)prop-2-enoyl]phenyl}-benzenesulfonamide (2).

, 2015
1 Retention time.2 Mobile phase used: CH3CN:aqueous buffer containing chloroacetic acid 0.1% (55:45).Yield, physical state, melting point, purity, and spectroscopic data (GS-MS, IR, 1H-NMR) of N-(4-acetylphenyl)benzenesulfonamide (1) and N-{4-[(E)-3-(4 ...
Carolina Ribeiro e Silva (791907), Caridad Noda Perez (791910), Daniela de Melo e Silva (604342), Lee Chen-Chen (791911), Aline Bernardes (791909), Flávio Fernandes Veloso Borges (791908)   +5 more
core   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Intracellular Bacterial Targeting by a Thiazolyl Benzenesulfonamide and Octaarginine Peptide Complex

, 2022
A brominated thiazolyl benzenesulfonamide (BTB) derivative is conjugated with the cell-penetrating peptide octaarginine (R8) in an effort to construct innovative antibacterial products.
Poonam Ratrey (9158598), Bhaskar Datta (473077), Abhijit Mishra (1910602)   +2 more
core   +2 more sources

Biospecific binding of carbonic anhydrase to mixed SAMs presenting benzenesulfonamide ligands: A model system for studying lateral steric effects

, 1999
This work describes the binding of carbonic anhydrase (CA) to mixed self-assembled monolayers (SAMs) presenting benzenesulfonamide ligands at a surface consisting primarily of tri(ethylene glycol) [(EG)(3)OH] groups.
Whitesides, GM, Carbeck, JD, Lahiri, J, Isaacs, L, Grzybowski, B   +4 more
core   +1 more source