Results 131 to 140 of about 8,103 (214)

Rearrangement Reaction Based on the Structure of N‑Fluoro‑N‑alkyl Benzenesulfonamide

, 2018
A novel rearrangement reaction based on the structure of N-fluoro-N-alkyl benzenesulfonamide was developed. The reaction proceeded readily at 50 °C in formic acid and generated a variety of benzenesulfonamides and aldehydes or ketones simultaneously. The
Han-Ying Wang (3193443), Xiao-Qiu Pu (5842394), Xian-Jin Yang (1633231)   +2 more
core   +1 more source

The Structure of Benzenesulfonamide-Terminated Thiol on Gold Surfaces and the Interaction with Carbonic Anhydrase

A well-structured and robust biomolecular monolayer based upon a benzenesulfonamideterminated alkane thiol, to be used as a model system for molecular recognition processes, was prepared.
Linares, Mathieu,, Skoglund, Caroline,, Uvdal, Jahsa,, Vahlberg, Cecilia,, Norman, Patrick,   +4 more
core  

Synthesis of Some Derivatives of p-(1,l-Dioxotetrahydro-2- thiazinyl) benzenesulfonamide

, 1966
The anticonvulsant drug p-(1,l-dioxotetrahydro-2-thiazinyl) benzenesulfonamide (1)1, although structurally different from classical anticonvulsant drugs, was found to be active in psychomotor seizures or epileptic ...
Glunčić, B., B. Glunčić, A. Junašević-Holjevac, Junašević-Holjevac, A.   +3 more
core  

A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors

, 2011
The design, synthesis and delivery potential of a new type of benzenesulfonamide cyclo-oxygenase-2 (COX-2) inhibitor prodrug is investigated using celecoxib.
KEOGH, BRIAN, WINDLE, HENRY, GILMER, JOHN FRANCIS, KELLEHER, DERMOT P, REILLY, MARY   +4 more
core  

Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide

4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide is a new selective type II carbonic anhydrase inhibitor with local action through instillation into the eyes.
Efimova, Yu. A., Shetnev, A. A., Yaichkov, I. I., Khokhlov, A. L., Panova, V. A.   +4 more
core   +1 more source

Combinatorial chemistry identifies additional compounds that selectively inhibit DLK-dependent retrograde signaling while minimally affecting other axonal roles of DLK. [PDF]

Sci Rep
Zhang X, Jeong H, Melenski E, Gordon J, Childers WE, Thomas GM.   +5 more
europepmc   +1 more source

Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity. [PDF]

J Med Chem
Roshdy E, Kilic A, Mustafa M, Celik I, Sarı ZB, Simsek E, Nocentini A, Giovannuzzi S, Supuran CT, Özensoy Güler Ö, Winum JY, Abe M.   +11 more
europepmc   +1 more source

Photochemical Catalyst-Free Synthesis of Pyrrolidines via a Hofmann-Loffler-Freytag Reaction. [PDF]

Molecules
Shkembi ASJ, Pasqualon L, Serviou SK, Lantzanakis MVG, Kokotos CG.   +4 more
europepmc   +1 more source

Correction to "Intracellular Binding of Novel Fluorinated Compounds to Carbonic Anhydrase Isoforms Explored by In-Cell ¹⁹F NMR". [PDF]

J Med Chem
Costantino A, Barbieri L, Giovannuzzi S, Nocentini A, Supuran CT, Raitelaitis M, Nordlund P, Banci L, Luchinat E.   +8 more
europepmc   +1 more source

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity. [PDF]

Mol Med Rep
Dhulkifle H, Therachiyil L, Hasan MH, Younis SM, Al-Shar'i NA, Yalcin HC, Maayah ZH.   +6 more
europepmc   +1 more source