Conformation of nucleosides: circular dichroism study on the syn-anti conformational equilibrium of 2-substituted benzimidazole nucleosides. [PDF]
Daniel W. Miles+3 more
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Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik+20 more
wiley +1 more source
Novel benzimidazole hybrids: design, synthesis, mechanistic studies, antifungal potential and molecular dynamics. [PDF]
Ibrahim AA+4 more
europepmc +1 more source
Application of the Horner Reaction to Benzimidazoles
Tadashi Sasaki, Moriyasu Ando
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A Convenient Synthesis of Naphth[2′,3′ : 5,6]- and [1′,2′ : 5,6]-1,3-oxazino[3,2-b]benzimidazoles and Benzoxazolo[3,2-b] [l,3]quinazolone - Mechanism of Thiophosgene Heteroeyelisation [1] [PDF]
Shikha Dubey+2 more
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Abstract Background and Aims The use of new synthetic opioids, such as the highly potent 2‐benzylbenzimidazoles (i.e. nitazene) drugs, is a global health concern because of their increased risk of fatal overdose. In the early 2020s, nitazene analogues were linked to significant numbers of overdoses in the United States.
Richard Bade+5 more
wiley +1 more source
Immobilization of CuO onto melamine functionalized magnetic nanocomposite: an efficient catalyst for the Preparation of benzimidazole compounds. [PDF]
Asdollahpour Z, Baharfar R, Asghari S.
europepmc +1 more source
Gas-Liquid Chromatographic Determination of Thiabendazole and Methyl 2-Benzimidazole Carbamate in Fruits and Crops [PDF]
Gwan H Tjan, John T A Jansen
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Progress on the development of Class A GPCR‐biased ligands
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales+20 more
wiley +1 more source
Hybrid <i>Bis</i>-(Imidazole/Benzimidazole)-Pyridine Derivatives with Antifungal Activity of Potential Interest in Medicine and Agriculture via Improved Efficiency Methods. [PDF]
Balaes T+5 more
europepmc +1 more source