Results 171 to 180 of about 13,035 (231)
Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines [PDF]
Molecular Diversity, 2012 Three scaffolds of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines were synthesized via Ugi/de-protection/cyclization methodology. Benzimidazole forming ring closure was enabled under microwave irradiation in the presence of 10% TFA/DCE.
Zhi-Gang Xu +2 more
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Journal of the American Veterinary Medical Association, 1981
SUMMARY The effectiveness of 1 pro-benzimidazole (pro-bzd) drug, 3 benzimidazole (bzd) drugs, and 3 non-benzimidazole (non-bzd) drugs in keeping fecal egg counts below 50 eggs per gram 2 and 4 weeks after treatment at 6-week intervals was compared in groups of brood mares and yearlings at 2 Standardbred farms.
R P, Herd, T B, Miller, A A, Gabel
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SUMMARY The effectiveness of 1 pro-benzimidazole (pro-bzd) drug, 3 benzimidazole (bzd) drugs, and 3 non-benzimidazole (non-bzd) drugs in keeping fecal egg counts below 50 eggs per gram 2 and 4 weeks after treatment at 6-week intervals was compared in groups of brood mares and yearlings at 2 Standardbred farms.
R P, Herd, T B, Miller, A A, Gabel
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The chromatography of benzimidazoles
Journal of Chromatography A, 1973Summary The thin-layer chromatography of a series of mono- and bis-benzimidazoles has been studied in order to determine the influence of substituents. Results for the gas-liquid chromatography of 2-alkyl-substituted benzimidazoles and their silyl derivatives show that a quasi-exponential relationship exists between retention time and the carbon ...
E R, Cole, G, Crank, A S, Sheikh
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METABOLISM OF BENZIMIDAZOLE IN WHEAT: I. FORMATION OF BENZIMIDAZOLE NUCLEOTIDE
Canadian Journal of Biochemistry, 1965An enzyme, probably benzimidazole nucleotide:pyrophosphate phosphoribosyl transferase, has been demonstrated in the 33–65% (NH4)2SO4fraction of wheat embryos. The enzyme was assayed indirectly by the apparent inhibition of the analogous orotidine-5′-phosphate pyrophosphorylase caused by benzimidazole competing with orotate for P-ribosyl-PP.
M, KAPOOR, E R, WAYGOOD
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The metabolism of benzimidazole anthelmintics
Parasitology Today, 1990The benzimidazole carbamates are important broad-spectrum drugs for the control of helminth parasites in mammals. David Gottschall, Vassilios Theodorides and Richard Wang explain that the metabolism of these compounds depends heavily on the substituent present on carbon-5 of the benzimidazole nucleus and involves a wide variety of reactions.
D W, Gottschall +2 more
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Biochemistry of benzimidazole resistance
Acta Tropica, 1994Heavy reliance on the benzimidazole (BZ) anthelmintics since their introduction in the 1960's for the control of gastrointestinal parasites of livestock has led to widespread BZ resistance in target parasite species. The BZs exert their primary action by binding to tubulin, the major protein component of microtubules.
E, Lacey, J H, Gill
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Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin
Biochimica et Biophysica Acta (BBA) - General Subjects, 1978The binding and inhibitory properties of 11 benzimidazoles for bovine brain tubulin were investigated. The effects of the benzimidazoles on the initial rates of microtubule polymerization were determined by a turbidimetric assay. The median inhibitory concentrations (I50) for nocodazole, oxibendazole, parbendazole, mebendazole and fenbendazole ranged ...
P A, Friedman, E G, Platzer
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