Results 101 to 110 of about 12,797 (181)
PharmaceuticalsBackground/Objectives: The Trypanosoma cruzi infection promotes an intense inflammatory process that affects several tissues. The cholinergic system may exert a regulatory immune response and control the inflammatory process. This study aimed to evaluate
Aniélen D. da Silva +19 more
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Benznidazole-Loaded Polymeric Nanoparticles for Oral Chemotherapeutic Treatment of Chagas Disease
PharmaceuticsChagas disease (CD) is a worldwide public health problem. Benznidazole (BZ) is the drug used to treat it. However, in its commercial formulation, it has significant side effects and is less effective in the chronic phase of the infection. The development
Lucas Resende Dutra Sousa +9 more
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The genetics and genomics of Trypanosoma cruzi [PDF]
, 2007 Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
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Chagas Disease: “The Kiss of Death” [PDF]
, 2015 Chagas disease is a vector transmitted disease also known as American trypanosomiasis. Chagas disease is classified as a protist or protozoa, which is a simplified version of ‘animal-like single celled organism that is like a multicellular organism ...
Castro, Stacy, Rogers, Jessica
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Recent advances in the treatment of Chagas disease [PDF]
, 2013 Descoberta há cem anos, a doença de Chagas afeta a mais de quinze milhões de pessoas em toda a América Latina e, ainda hoje, não há tratamentoeficaz. O fármaco benznidazol, utilizado como única opção de tratamento no Brasil, é ineficaz na fase crônica da
da Cunha Filho, Marcílio Sérgio Soares +4 more
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Chagas Disease in the Non-Endemic Area of Rome, Italy: Ten Years of Experience and a Brief Overview
Infectious Disease ReportsChagas disease (CD) is a parasitic infection endemic in Latin America and also affects patients in Western countries due to migration flows. This has a significant impact on health services worldwide due to its high morbidity and mortality burden.
Maria Letizia Giancola +14 more
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Doença de Chagas: Contribuições do Centro de Investigações Toxicológicas [PDF]
, 2015 La quimioterapia de la enfermedad de Chagas cuenta en la actualidad con el empleo de dos fármacos solamente: Nifurtimox y Benznidazol. Nifurtimox es un nitrofurano y Benznidazol es un compuesto nitroimidazólico. El uso de estas drogas para tratar la fase
Castro, Gerardo Daniel +3 more
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Tolerance and Safety of Nifurtimox in Patients with Chronic Chagas Disease [PDF]
, 2017 Background. Nifurtimox has been used to treat Chagas disease for 40 years, but tolerance and safety data in adults are scarce. We aimed to evaluate nifurtimox tolerance and safety in a cohort of Trypanosoma cruzi-infected adult patients in a country of ...
Alirol, Emilie +5 more
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Biological Research, 2004 Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease.
JUAN DIEGO MAYA +7 more
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