Results 121 to 130 of about 12,797 (181)

Identification of Novel <i>Trypanosoma cruzi</i> Cysteine Protease Inhibitors via Ligand-Based Virtual Screening of FDA-Approved Drugs with Trypanocidal Activity. [PDF]

Diseases
Vázquez-Jiménez LK, González-González A, Delgado-Maldonado T, Gómez-Escobedo R, Nogueda-Torres B, Martínez-Vázquez AV, Ortiz-Pérez E, Aguirre-Alvarado C, Alcántara-Farfán V, Cordero-Martínez J, Rodríguez-Páez L, Moreno-Rodriguez A, Rivera G.   +12 more
europepmc   +1 more source

Priority without progress: the FDA's neglected tropical disease voucher program after 18 years. [PDF]

Health Aff Sch
Goh M, Outterson K, Kesselheim AS.
europepmc   +1 more source

Induced pluripotent stem cell-derived human macrophages as an infection model for Trypanosoma cruzi. [PDF]

PLoS Negl Trop Dis
Baert L, Cal M, Doll T, Müller M, Mäser P, Kaiser M.   +5 more
europepmc   +1 more source

Evaluation of the autonomic nervous system in autochthonous patients from Amazon with acute Chagas disease treated with benznidazole. [PDF]

PLoS Negl Trop Dis
Hosannah da Silva E Silva MR, de Sousa DRT, Ortiz JV, Monteiro MM, Brandão ARJ, Silva E Silva MR, Smith-Doria S, Cavalcante MSM, Couceiro KDN, Arêas GPT, de Oliveira Guerra JA, Guerra MDGVB, Ferreira JMBB.   +12 more
europepmc   +1 more source

Ruthenium Complexes Containing Thiobenzamide Act as Potent and Selective Anti-<i>Trypanosoma cruzi</i> Agents through Apoptotic Cell Death. [PDF]

ACS Infect Dis
das Neves MVG, Cezar IS, Dos Santos Rodrigues E, Bomfim FCT, Duarte RDS, Campos de Souza CV, Rocha VPC, de Sá DS, Santos-Filho OA, da Silva CDS, Soares MBP, Meira CS.   +11 more
europepmc   +1 more source

Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States. [PDF]

Open Forum Infect Dis
Alperin C, Nguyen N, Duffey M, Clark EH.
europepmc   +1 more source

Asymptomatic Trypanosoma cruzi Infection Identified During Blood Donation Screening. [PDF]

Cureus
Ngo JM, Maknojiya AN, Patel RY, Meza A.
europepmc   +1 more source

Transcriptomic and ultrastructural responses to Amiodarone-Itraconazole in naturally benznidazole-resistant and -susceptible Trypanosoma cruzi strains. [PDF]

PLoS Negl Trop Dis
Gutiérrez S, Ospina C, Cáceres T, Patiño LH, Paniz-Mondolfi A, Ramírez JD.   +5 more
europepmc   +1 more source

Synthesis and Antitrypanosomal Activity of Novel 2‑Nitroimidazole-3,5-Disubstituted Isoxazole Derivatives with Diaryl Ether and Thioether Substituents. [PDF]

ACS Omega
Santos LBB, Carvalho DB, Shiguemoto CYK, Lacerda OD, Silva TS, Portapilla GB, Silva-Filho SE, Guerrero PG, de Albuquerque S, Baroni ACM.   +9 more
europepmc   +1 more source

Benznidazole Treatment

As the development of new drugs for Chagas disease is not a priority due to its neglected disease status, an option for increasing treatment adherence is to explore alternative treatment regimens, which may decrease the incidence of side effects. Therefore, we evaluated the efficacy of different therapeutic schemes with benznidazole (BNZ) on the acute ...
Fonseca, Kátia da Silva, Perin, Luísa, de Paiva, Nívia Carolina Nogueira, da Silva, Beatriz Cristiane, Duarte, Thays Helena Chaves, Marques, Flávia de Souza, Costa, Guilherme de Paula, Molina Romero, Israel||, Correa-Oliveira, Rodrigo||, Vieira, Paula Melo de Abreu||, Carneiro, Cláudia Martins||   +10 more
openaire   +1 more source