Results 161 to 170 of about 56,478 (190)
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Antibody stimulation of benzo(a)pyrene carcinogenesis
Cancer Letters, 1978Benzo(a)pyrene (BP) was conjugated to horse serum albumin (HSA) and then attached to aldehyde fixed human erythrocytes. These cells were used in a passive hemagglutination test to measure BP antibody. BP antibodies were found to be induced in Swiss mice injected with tumorigenic doses of BP.
G L, Curtis, W L, Ryan, F, Stenbäck
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Free radicals derived from benzo[a]pyrene
Biochemical and Biophysical Research Communications, 1976Abstract At least four different free radicals can be formed from benzo[a]pyrene under different reaction conditions, namely the 6-oxybenzo[a]pyrene radical, the benzo[a]pyrene anion and cation radicals and a radical from heated benzo[a]pyrene. The formation and esr spectra of these radicals have been studied with the aim of clarifying the nature of ...
E M, Menger, R B, Spokane, P D, Sullivan
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Benzo(a)pyrene in Brazilian vegetable oils
Food Additives and Contaminants, 1996Samples of vegetable oils on the Brazilian market including rape seed, corn, soybean, sunflower, rice, palm and garlic were analysed for benzo(a)pyrene (B(a)P). The analytical method involved liquid-liquid extraction, clean-up on silica gel column and determination by high performance liquid chromatography using fluorescence detection.
A M, Pupin, M C, Toledo
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Benzo(a)pyrene diolepoxide-haemoglobin and albumin adducts at low levels of benzo(a)pyrene exposure
Biomarkers, 2000A biomonitoring study was conducted to simultaneously measure individual benzo(a)pyrene (BaP) exposure in 50 office employees, not occupationally exposed to polycyclic aromatic hydrocarbons (PAH), using personal samplers and the formation of (+) r-7, t-8-dihyroxy-t-9,t-10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene (BPDE) adducts to haemoglobin (BPDE-Hb ...
R. Pastorelli +7 more
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2014
Cigarette smoking is the leading cause of preventable death in the United States. While there are more than 4,000 chemicals found in tobacco smoke, the polycyclic aromatic hydrocarbons (PAHs) have been clearly demonstrated to contribute to smoking-related cancers.
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Cigarette smoking is the leading cause of preventable death in the United States. While there are more than 4,000 chemicals found in tobacco smoke, the polycyclic aromatic hydrocarbons (PAHs) have been clearly demonstrated to contribute to smoking-related cancers.
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Wheat Bran and the Induction of Intestinal Benzo(a)pyrene Hydroxylase by Dietary Benzo(a)pyrene
The Journal of Nutrition, 1989The mucosa of the intestine responds to polycyclic aromatic hydrocarbons (PAH) with the rapid induction of benzo(a)pyrene hydroxylase (BPH). Studies were conducted to determine if dietary fiber would reduce exposure of the intestine to dietary benzo(a)pyrene (BP) as indicated by intestinal BPH activity.
S K, Clinton, W J, Visek
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Analytical and Bioanalytical Chemistry, 2016
A first gas chromatography-tandem mass spectrometry (GC-MS/MS) method was designed for analysis of four tetrahydroxylated benzo[a]pyrene metabolites (benzo[a]pyrene-r-7,t-8,t-9,c-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,t-9,t-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,c-9,c-10-tetrahydrotetrol, and benzo[a]pyrene-r-7,t-8,c-9,t-10-tetrahydrotetrol ...
Nathalie, Grova +3 more
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A first gas chromatography-tandem mass spectrometry (GC-MS/MS) method was designed for analysis of four tetrahydroxylated benzo[a]pyrene metabolites (benzo[a]pyrene-r-7,t-8,t-9,c-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,t-9,t-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,c-9,c-10-tetrahydrotetrol, and benzo[a]pyrene-r-7,t-8,c-9,t-10-tetrahydrotetrol ...
Nathalie, Grova +3 more
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Radioimmunoassay for benzo[a]pyrene.
Journal of the National Cancer Institute, 1978A benzo[a]pyrene (BP)-bovine serum albumin conjugate was synthesized and used to immunize 2.5- to 3.0-kg New Zealand White rabbits. The resulting antisera to BP bound trace amounts of [3H] (55 pg; 6,000 counts/min). A radioimmunoassay (RIA) to BP was developed by the antiserum first being titered with the [3H]BP and then a standard curve being ...
N Y, Kado, E T, Wei
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Tumorigenesis by Benzo(a)pyrene Administered Intracolonically
Oncology, 1980Benzo(a)pyrene (BP) was administered to Swiss mice in 1 and 10 weekly intracolonic instillations at 200 microgram/g body weight. The single administration of BP induced a statistically significant incidence of malignant lymphomas and tumors of the forestomach, while its repeated instillation, evoked, in addition to these two tumor types, neoplasms in ...
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The dual effects of Benzo(a)pyrene/Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide on DNA Methylation
Science of The Total EnvironmentBenzo(a)pyrene (BaP) is one of the most thoroughly studied polycyclic aromatic hydrocarbons(PAHs) and a widespread organic pollutant in various areas of human life. Its teratogenic, immunotoxic and carcinogenic effects on organisms are well documented and widely recognized by researchers.
Cheng, Zhao +5 more
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