Results 1 to 10 of about 255 (109)

"Golden" Cascade Cyclization to Benzo[c]-Phenanthridines. [PDF]

Chemistry, 2021
AbstractHerein, we describe a gold‐catalyzed cascade cyclization of Boc‐protected benzylamines bearing two tethered alkyne moieties in a domino reaction initiated by a 6‐endo‐dig cyclization. The reaction was screened intensively, and the scope was explored, resulting in nine new Boc‐protected dihydrobenzo[c]phenanthridines with yields of up to 98 ...
Hendrich CM, Senn S, Haas L, Hoffmann MT, Zschieschang U, Greiner LC, Rominger F, Rudolph M, Klauk H, Dreuw A, Hashmi ASK.   +10 more
europepmc   +4 more sources

Practical and modular construction of benzo[c]phenanthridine compounds

Science China Chemistry, 2022
AbstractHere, we describe a general and modular strategy for the rapid assembly of benzo[c]phenanthridine (BCP) derivatives using homogeneous gold catalysis. Notably, in contrast to traditional methods based on the specially preformed substrates that have an inherent preference for the formation of this class of compounds with limited flexibility, this
Cheng Zhang, Qian Chen, Lei Wang, Qiaoying Sun, Yangyang Yang, Matthias Rudolph, Frank Rominger, A. Stephen K. Hashmi   +7 more
openaire   +1 more source

Total Synthesis of Oxyfagaronine, Phenolic Benzo[c]phenanthridine and General Synthetic Way of 2,3,7,8‐ and 2,3,8,9‐Tetrasubstituted Benzo[c]phenanthridine Alkaloids.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thanh Nguyen, Le, Won-Jea, Cho
openaire   +3 more sources

Synthesis of fagaridine, a phenolic benzo (c) phenanthridine alkaloid.

Chemical and Pharmaceutical Bulletin, 1985
Regioselective demethylation of oxychelerythrine (5), derived from berberine (4), with p-toluenesulfonic acid in refluxing toluene gave oxyfagaridine (6), which was converted into fagaridine (1) in good yields by successive reduction and oxidation.
Miyoji Hanaoka, Hiroshi Yamagishi, Chisato Mukai   +2 more
openaire   +3 more sources

Transformation of Phthalideisoquinoline Alkaloid to Benzo [c] phenanthridine Alkaloid

Chemical and Pharmaceutical Bulletin, 1972
l-α-Narcotine is easily converted into dihydroprotoberberine methiodide. The Hofmann degradation of this methiodide gives methine base which is transformed to benzo [c] phenanthridine derivative by photocyclization and dehydrogenation.
MASAYUKI ONDA, KENSHIRO KAWAKAMI
openaire   +2 more sources

Difluoromethylborates and Muonium for the Study of Isonitrile Insertion Affording Phenanthridines via Imidoyl Radicals. [PDF]

J Org Chem, 2023
Konagaya K, Huang YE, Iwami K, Fujino T, Abe R, Parchment-Morrison R, Kojima KM, McKenzie I, Ito S.   +8 more
europepmc   +1 more source

The Effective Synthesis of New Benzoquinoline Derivatives as Small Molecules with Anticancer Activity. [PDF]

Pharmaceuticals (Basel), 2023
Zbancioc G, Mangalagiu II, Moldoveanu C.
europepmc   +1 more source

I₂-mediated Csp²-P bond formation via tandem cyclization of o-alkynylphenyl isothiocyanates with organophosphorus esters. [PDF]

RSC Adv, 2022
Liu Y, Wu W, Sang X, Xia Y, Fang G, Hao W.   +5 more
europepmc   +1 more source

Structural modifications of berberine and their binding effects towards polymorphic deoxyribonucleic acid structures: A review. [PDF]

Front Pharmacol, 2022
Fu L, Mou J, Deng Y, Ren X.
europepmc   +1 more source

Metal-Free Synthesis of N-Heterocycles via Intramolecular Electrochemical C-H Aminations. [PDF]

Front Chem, 2022
Wang H, Zheng Y, Xu H, Zou J, Jin C.
europepmc   +1 more source