Results 21 to 30 of about 255 (109)

Ortho Arylation of N‐Aryl Amides and the Construction of Diagonal Tetraarylbenzenediamines and N‐Doped Fulminenes via BBr3‐Derived Dibromoboracycles

Chemistry – A European Journal, Volume 31, Issue 8, February 6, 2025.
We report the discovery of a boron‐driven ortho‐arylation reaction of N‐aryl amides and ureas. This novel method enables directed borylation of a wide range of substrates, leading to the synthesis of unique compounds such as N‐doped fulminene and diagonal tetraarylbenzenediamines.
Ganesh H. Shinde, Ganesh S. Ghotekar, Henrik Sundén   +2 more
wiley   +1 more source

Pioneering Metal‐Free Late‐Stage C−H Functionalization Using Acridinium Salt Photocatalysis

Chemistry – A European Journal, Volume 30, Issue 67, December 2, 2024.
Organic dyes are powerful photocatalysts in organic transformations due to their availability, adaptable absorption, and diverse structures. Acridinium‐based organo‐photocatalysts, notable for visible light responsiveness, efficiently functionalize inert C−H bonds under mild conditions without transition metals.
Shyamal Kanti Bera, Andrea Porcheddu
wiley   +1 more source

Active Site Engineering in Reticular Covalent Organic Frameworks for Photocatalytic CO2 Reduction

Advanced Functional Materials, Volume 34, Issue 43, October 22, 2024.
Herein, different strategies for active site engineering in covalent organic frameworks are comprehensively analyzed and categorized as photocatalysts for reduction of CO2. The synthetic rationale and resulting catalytic activity for various approaches including framework engineering and grafting of transition metal active sites as well as metal free ...
Bibhuti Bhusan Rath, Simon Krause, Bettina Valeska Lotsch   +2 more
wiley   +1 more source

α‐Halocarbonyls as a Valuable Functionalized Tertiary Alkyl Source

ChemistryOpen, Volume 13, Issue 10, October 2024.
In this review, we introduce α‐bromocarbonyl compounds as tertiary alkyl sources that act as both nucleophiles and electrophiles. Although α‐bromocarbonyl compounds have been used as radical initiators in the past, their use as organic synthesis reactants only began to take off around 2012. Abstract This review introduces the synthetic organic chemical
Takashi Nishikata
wiley   +1 more source

Synthesis, Characterization, and Cytotoxicity Evaluation of Novel Water‐Soluble Cationic Platinum(II) Organometallic Complexes with Phenanthroline and Imidazolic Ligands

Chemistry – A European Journal, Volume 30, Issue 38, July 5, 2024.
We reported the synthesis of monofunctional platinum(II) complexes for anticancer evaluation. Remarkably, complex 4 demonstrated the most pronounced cytotoxicity across both cancer (HeLa and Caki‐1) and normal cell lines (HK‐2). In contrast, complex 3 displayed superior selectivity for tumor cells (Caki‐1) compared to healthy cells (HK‐2) among the ...
Asjad Ali, Erika Stefàno, Federica De Castro, Giuseppe Ciccarella, Gianluca Rovito, Santo Marsigliante, Antonella Muscella, Michele Benedetti, Francesco Paolo Fanizzi   +8 more
wiley   +1 more source

Electrophilicity Modulation for Sub‐ppm Visualization and Discrimination of EDA

Advanced Science, Volume 11, Issue 18, May 15, 2024.
A novel sensing strategy based on a unique differentiated‐nucleophilic mechanism is established with a boosted response to trace EDA either in liquid or gas and a distinguishable response for its structure analog—N2H4. This design concept is displayed as a telescope with tiny nucleophilicity discrimination ability toward the yachts labeled with EDA or ...
Hao Zhao, Yuan Liu, Gaosheng Li, Da Lei, Yuwan Du, Yudong Li, Hui Tang, Xincun Dou   +7 more
wiley   +1 more source

Diazo Quinone: An Effective Phenolic Precursor for Building C(sp2)−C(sp2) Bonds

Asian Journal of Organic Chemistry, Volume 13, Issue 5, May 2024.
Diazo quinone has emerged as an effective phenolic precursor in construction of C(sp2)−C(sp2) bonds, offering new avenues for accessing valuable phenolic biaryls and styryls compounds. This review highlights recent advancements in metal‐catalyzed quinoid‐carbene C(sp2)−H insertion reactions and transition‐metal‐free cross‐coupling reactions of diazo ...
Kai Wu, Chi‐Ming Che
wiley   +1 more source

Tandem Hydrogen‐Borrowing Dehydrogenative Coupling and Hydrodefluorination

Advanced Synthesis &Catalysis, Volume 366, Issue 8, Page 1809-1819, April 23, 2024.
Abstract Dehydrogenative coupling (DC) is an attractive approach to constructing new C−N bonds using alcohols as electrophiles. In ‘hydrogen‐borrowing’ variants of DC, the H2 liberated can be used to re‐hydrogenate unsaturated intermediates to produce saturated products.
Baldeep K. Sidhu, Rajarshi Mondal, David E. Herbert   +2 more
wiley   +1 more source

Visible‐Light‐Driven Cyclizations

Advanced Synthesis &Catalysis, Volume 366, Issue 4, Page 635-697, February 20, 2024.
Abstract In recent years, the interest to develop cyclizations promoted by visible light has been gaining a lot of attention due to its sustainability aspect. In this review, we summarize the most important advances in this period by describing the methods used to generate different ring sizes, while focusing on the mechanistic details of these ...
Emilia Oueis, Mirella Elkadi, Ramon Rios
wiley   +1 more source

Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase. [PDF]

Pharmaceuticals (Basel), 2023
Battisti UM, Monjas L, Akladios F, Matic J, Andresen E, Nagel CH, Hagkvist M, Håversen L, Kim W, Uhlen M, Borén J, Mardinoğlu A, Grøtli M.   +12 more
europepmc   +1 more source