Results 191 to 200 of about 123,980 (206)

Adverse Events Associated with Flumazenil Treatment for the Management of Suspected Benzodiazepine Intoxication--A Systematic Review with Meta-Analyses of Randomised Trials.

Basic & Clinical Pharmacology & Toxicology, 2016
Flumazenil is used for the reversal of benzodiazepine overdose. Serious adverse events (SAEs) including seizures and cardiac arrhythmias have been reported in patients treated with flumazenil, and the clinical advantage of flumazenil treatment has been ...
E. Penninga, N. Graudal, M. Ladekarl, G. Jürgens   +3 more
semanticscholar   +1 more source

Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial.

JAMA Internal Medicine, 2014
IMPORTANCE The American Board of Internal Medicine Foundation Choosing Wisely Campaign recommends against the use of benzodiazepine drugs for adults 65 years and older.
C. Tannenbaum, Philippe Martin, R. Tamblyn, A. Benedetti, Sara Ahmed   +4 more
semanticscholar   +1 more source

Benzodiazepine receptor: demonstration in the central nervous system

Science, 1977
Diazepam, a potent minor tranquilizer, binds with high affinity to a specific benzodiazepine receptor that occurs exclusively in the central nervous system. The receptor is mainly localized in the synaptic membrane fraction.
H. Möhler, T. Okada
semanticscholar   +1 more source

Benzodiazepine use and risk of mortality among patients with schizophrenia: a retrospective longitudinal study.

Journal of Clinical Psychiatry, 2016
OBJECTIVE This study examined the association between benzodiazepine use alone or in combination with antipsychotics and risk of mortality in patients with schizophrenia. METHODS A retrospective longitudinal analysis was performed using Medicaid claims
C. Fontanella, J. Campo, G. Phillips, Danielle L. Hiance-Steelesmith, Helen Anne Sweeney, Kwok Tam, D. Lehrer, R. Klein, M. Hurst   +8 more
semanticscholar   +1 more source

Why won’t it stop? The dynamics of benzodiazepine resistance in status epilepticus

Nature Reviews Neurology, 2022
R. Burman, R. Rosch, J. Wilmshurst, Arjune Sen, G. Ramantani, C. Akerman, J. V. Raimondo   +6 more
semanticscholar   +1 more source

Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia or bipolar disorder: A randomised, placebo-controlled, blinded trial

World Journal of Biological Psychiatry, 2016
Objectives. We assessed if prolonged-release melatonin can facilitate withdrawal of long-term benzodiazepine usage in patients with schizophrenia or bipolar disorder. Methods.
L. Baandrup, J. Lindschou, P. Winkel, C. Gluud, B. Glenthøj   +4 more
semanticscholar   +1 more source

Is there really a link between benzodiazepine use and the risk of dementia?

Expert Opinion on Drug Safety, 2015
Introduction: Several studies have highlighted an increased risk of dementia in benzodiazepine users. As dementia incidence and benzodiazepine use are both high, particularly in the elderly, even a moderate increase in this risk would induce a tremendous
Sophie Billioti de Gage, A. Pariente, B. Bégaud   +2 more
semanticscholar   +1 more source

The Benzodiazepine Binding Sites of GABAA Receptors.

TIPS - Trends in Pharmacological Sciences, 2018
E. Sigel, M. Ernst
semanticscholar   +1 more source

A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias

CNS Drugs, 2018
Ross Penninkilampi, G. Eslick
semanticscholar   +1 more source

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.

TIPS - Trends in Pharmacological Sciences, 2006
V. Papadopoulos, M. Baraldi, T. Guilarte, T. Knudsen, J. Lacapere, P. Lindemann, M. Norenberg, D. Nutt, Abraham Weizman, Ming-Rong Zhang, M. Gavish   +10 more
semanticscholar   +1 more source