Results 141 to 150 of about 97,224 (305)

Leveraging Isomerization of Azo Dyes and Imines for the Facile Synthesis of Oxadiazepines and Related Heterocycles

Journal of Heterocyclic Chemistry, EarlyView.
A robust method for synthesizing substituted oxadiazepines and related heterocycles via intramolecular SNAr is detailed. Under mild conditions, this methodology has been leveraged to afford products of varying electronic and aryl nature in up to 99% yields.
Matthew W. Reeves, Christian A. Guzman, Herbi Yuliantoro, Peng Li, Elizabeth R. Young   +4 more
wiley   +1 more source

Benzodiazepines and traffic safety:forensic, analytical-toxicological and epidemiological aspects of driving under the influence of benzodiazepines

, 2008
Driving under the influence of alcohol, illicit and medicinal drugs (e.g. benzodiazepines) is under discussion world-wide because many studies have shown that its use is associated with impaired driving and increased accident risk despite sometimes ...
Smink, Beitske Eelkje
core   +1 more source

Addressing in‐hospital substance use: A bioethical evaluation of two possible approaches

Journal of Hospital Medicine, EarlyView.
Abstract Up to 40% of patients with substance use disorder report using non‐prescribed drugs when hospitalized. In‐hospital substance (IHSU) use is associated with poor outcomes and raises safety concerns for healthcare providers. Despite its prevalence, little guidance exists regarding best practices in responding to IHSU.
John C. Messinger, Taylor Baisey, Johanna Sluser, Benjamin A. Barsky, Marlene Martin, Leslie W. Suen   +5 more
wiley   +1 more source

Benzodiazepines: risks and benefits. A reconsideration

, 2014
Over the last decade there have been further developments in our knowledge of the risks and benefits of benzodiazepines, and of the risks and benefits of alternatives to benzodiazepines.
David S Baldwin (14158479), Sue Wilson (43053), Alan Bateson (16222097), H Valerie Curran (6629915), Brian Leonard (2684215), Katherine Aitchison (7592876), Simon Davies (606897), David J Nutt (6629912), Dai Stephens (16053440)   +8 more
core  

Sublingual Zolpidem for MRI in Claustrophobic Patients: A Prospective, Non‐Randomized Noninferiority Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Claustrophobia during MRI may lead to examination interruption, motion artifacts, prolonged acquisition time, and reduced diagnostic quality, frequently requiring intravenous sedation to ensure successful examination completion and adequate image acquisition.
Beatriz Birelli do Nascimento, Fernando de Sá Del Fiol, Marcus Vinicius Birelli do Nascimento, Lucas Bueno de Oliveira, Samanta Aparecida Alves, Lucas do Nascimento Bernardes   +5 more
wiley   +1 more source

Outcomes of pharmacist‐led deprescribing interventions in older adults living in long‐term care facilities: a scoping review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background An increase in the ageing population across long‐term care facilities (LTCFs) has led to an increased risk of polypharmacy. Pharmacist‐led deprescribing (PLD) can reduce these risks but there are limitations to its widespread uptake.
Sefunmi Odetola, Eileen Willis, Katrina Lane‐Krebs, Ashlyn Sahay   +3 more
wiley   +1 more source

A comparative analysis of the prevalence of medicine classes and polypharmacy between community‐dwelling and residential aged care populations in Western Australia

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim, Ninh Ha, David Youens, Rachael Moorin, Andrew Stafford   +4 more
wiley   +1 more source

Depressive symptom severity and treatment outcome in posttraumatic stress disorder following childhood trauma: A secondary analysis of a randomized clinical trial

Journal of Traumatic Stress, EarlyView.
Abstract Depressive symptoms are frequently comorbid with posttraumatic stress disorder (PTSD), yet it remains unclear whether depressive symptom severity before the start of treatment affects the results of trauma‐focused psychotherapy. We hypothesized that baseline depressive symptom severity might reduce overall PTSD symptom improvement and could ...
Lisanne M. Koomen, Mathijs L. Deen, Sophie A. Rameckers, Christopher W. Lee, Eva Fassbinder, Marleen M. Rijkeboer, Katrina L. Boterhoven de Haan, Arnoud Arntz   +7 more
wiley   +1 more source

Investigating the Pattern of Benzodiazepine Poisoning in Gorgan, 2008-2014

Journal of Clinical and Basic Research, 2018
Background and objectives: Benzodiazepine poisoning is one of the most important and common medical emergencies worldwide. The purpose of this study was to evaluate the pattern of poisoning with benzodiazepines in Gorgan, Iran.
Yaghoub Shayeste, Azam Delaram, Akram Pouyan Sadr, Jafar Jalilian, Danial Jafari   +4 more
doaj  

Z-Drugs and Benzodiazepines for Insomnia

Z-drugs are an appropriate first-line pharmacologic option for chronic insomnia — except in recent SUD. Consider benzodiazepines for severe insomnia unresponsive to multiple medication trials. When treating women with zolpidem, use lower doses.
Bhanu Prakash Kolla
core   +1 more source