Results 121 to 130 of about 158,750 (352)

Responding to Substance Use in Racialized Communities in Canada in the Current Polysubstance Era

Canadian Journal of Bioethics
Racialized people experience excess and preventable harm from substance use, raising questions about how justice ought to be pursued via health policy.
Manisha Pahwa, Chetan Mehta
doaj   +1 more source

Alexithymia in Anorexia Nervosa, More State Than Trait? A Multi‐Dimensional Assessment of Emotion Processing in Patients With Anorexia Nervosa, Recovered Patients and Healthy Controls

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Alexithymia is implicated in both development and maintenance of Anorexia Nervosa (AN). It is unclear what defines alexithymia in AN. In this study, emotion processing related to alexithymia was examined. Method 40 patients with AN, 43 recovered (RC) patients and 35 matched healthy controls (HC) filled out questionnaires on eating ...
E. Wezenberg, S. K. Peters, A. A. van Elburg, S. H. W. Mares   +3 more
wiley   +1 more source

Detecting benzodiazepine use through induced eye convergence inability with a smartphone app: a proof-of-concept study

Frontiers in Digital Health
BackgroundBenzodiazepines (BZDs) are readily available potent drugs that act as central depressants. These drugs are widely used, misused, and abused. For patients with BZD use disorder, the traditional sobriety monitoring method is periodic urine tests ...
Kiki W. K. Kuijpers, Markku D. Hämäläinen, Andreas Zetterström, Maria Winkvist, Marieke Niesters, Marieke Niesters, Monique van Velzen, Fred Nyberg, Albert Dahan, Albert Dahan, Albert Dahan, Karl Andersson, Karl Andersson   +12 more
doaj   +1 more source

Baclofen but Not Diazepam Alleviates Alcohol-Seeking Behavior and Hypothalamic–Pituitary–Adrenal Axis Dysfunction in Stressed Withdrawn Mice

Frontiers in Psychiatry, 2019
This study compares the impact of repeated injections of baclofen (an agonist of GABAB receptors) or diazepam (a benzodiazepine having an agonist action on GABAA receptors) given during the alcohol-withdrawal period on the stress-induced restoration of ...
Yolaine Rabat, Nadia Henkous, Marc Corio, Xavier Nogues, Daniel Beracochea   +4 more
doaj   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

Development of a Novel 18F‐Labeled Radioligand for Imaging Translocator Protein With Positron Emission Tomography

iRADIOLOGY, EarlyView.
Translocator protein 18 kDa (TSPO) is a well‐established biomarker of neuroinflammation and is implicated in the pathophysiology of various neurodegenerative diseases. This study presents [18F]TSPO‐1118 ([18F]3) as a promising positron emission tomography (PET) radioligand for imaging TSPO with high affinity, robust brain uptake, and specificity in ...
Jian Rong, Chunyu Zhao, Xin Zhou, Jiahui Chen, Yabiao Gao, Zhendong Song, Yinlong Li, Zijing Li, Steven H. Liang   +8 more
wiley   +1 more source

Effekten av samtidig forskrivning av benzodiazepiner for personer i legemiddelassistert rehabilitering: En systematisk oversikt [PDF]

, 2016
Key message Opioid maintenance treatment uses long acting opiates to reduce an opioid dependent person’s urge to take illicit opioid substances.
Ding, Yunpeng, Mosdøl, Annhild, Hov, Laila   +2 more
core  

Outcomes of pharmacist‐led deprescribing interventions in older adults living in long‐term care facilities: a scoping review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background An increase in the ageing population across long‐term care facilities (LTCFs) has led to an increased risk of polypharmacy. Pharmacist‐led deprescribing (PLD) can reduce these risks but there are limitations to its widespread uptake.
Sefunmi Odetola, Eileen Willis, Katrina Lane‐Krebs, Ashlyn Sahay   +3 more
wiley   +1 more source

A residue close to ?1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained

, 2010
Benzodiazepines act at the major isoforms of GABA type A receptors where they potentiate the current evoked by the agonist GABA. The underlying mechanism of this potentiation is poorly understood, but hypothesized to be related to the mechanism that ...
Sigel, Erwin, Benjamin P. Lüscher, Lüscher, Benjamin P, Lars Richter, Richter, Lars, Erwin Sigel, Roland Baur, Baur, Roland   +7 more
core   +1 more source

Hell's Itch: A Self‐Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Hell's itch is a severely distressing dermatological condition characterized by the onset of incessant itching and intolerable pain 2–3 days post‐sunburn. It is underdiagnosed and underreported, and no definitive management framework has yet been developed.
Kai Peter Moors, Willem I. Visser
wiley   +1 more source