Results 131 to 140 of about 97,224 (305)

Prescriptions for seizure cluster rescue therapy are not associated with decreased pediatric ED utilization

Epilepsia Open, EarlyView.
Abstract Objective Seizure clusters, or acute repetitive seizures, are a phenomenon often experienced by patients with epilepsy and pose a significant treatment challenge for clinicians. Several rescue medications have been approved by the Food and Drug Administration for the treatment of seizure clusters – including diazepam rectal gel, intranasal ...
Sarah A. Mangold, Mariah Eisner, Gabrielle Brown‐Mitchell, Christopher W. Beatty, Stephanie M. Ahrens, Jamie E. Twanow, Adam P. Ostendorf   +6 more
wiley   +1 more source

Hooked on benzodiazepines: GABAA receptor subtypes and addiction

, 2011
Benzodiazepines are widely used clinically to treat anxiety and insomnia. They also induce muscle relaxation, control epileptic seizures, and can produce amnesia.
Tan, Kelly R., Luescher, Christian, Christian Lüscher, Kelly R. Tan, Uwe Rudolph, Lüscher, Christian, Rudolph, Uwe, Tan, Kelly, Tan KR, Lüscher C, Rudolph U   +10 more
core   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

Prescribing of Benzodiazepines by Casualty Officers

, 1989
The prescribing of benzodiazepines by casualty officers in a busy district hospital over a three month period was examined by a retrospective review of case notes.
M B King, I D Nazareth
core   +1 more source

Effects of Concomitant Medications on Clinical and Immunological Outcomes of Cancer Patients Treated With Oncolytic Adenoviruses

International Journal of Cancer, EarlyView.
ABSTRACT Medication taken for other reasons than for the treatment of malignant disease, termed concomitant medication, is known to affect outcomes when used with immune checkpoint inhibitor therapy and other oncological drugs. However, no research in humans has addressed the relationship between concomitant medications and efficacy of oncolytic ...
Santeri A. Pakola, Tatiana V. Kudling, Nea Ojala, James H. A. Clubb, Victor Arias, Elise Jirovec, Mirte van der Heijden, Arianna Eleuteri, Lyna Haybout, Susanna Grönberg‐Vähä‐Koskela, Katriina Jalkanen, Tuomo Alanko, Matthew S. Block, Inge Marie Svane, Anna Kanerva, Otto Hemminki, Dafne C. A. Quixabeira, Claudia Kistler, Suvi Sorsa, Victor Cervera‐Carrascon, Akseli Hemminki   +20 more
wiley   +1 more source

Anxiety disorder and anxiolytic pharmacotherapy during pregnancy: The impact on pregnancy outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study determines the contributions of anxiety disorder and anxiolytic pharmacotherapy on perinatal outcomes and examines prescribing trends during pregnancy. Methods A retrospective cohort study was conducted at a single tertiary medical center between 2013 and 2024.
Sher Goaz Melet, Chagit Kliger, Daniel Gabbai, Danna Englender, Yariv Yogev, Omri Dominsky   +5 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Psychopharmacology in supportive care in cancer: a review for the clinician. I. Benzodiazepines

, 1999
Benzodiazepines are widely utilized in the cancer setting. Most aspects relevant to their use in supportive care are reviewed to assist the clinical oncologist in prescribing such drugs.
Mazzocato, C., Stiefel F, Stiefel, F., Berney, A., Berney A, Mazzocato C   +5 more
core   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

A Novel Application of the Volumetric Absorptive Micro Sampling Strategy to Quantify Dexmedetomidine in Capillary Blood Using an LC–MS/MS Method

Journal of Clinical Laboratory Analysis, EarlyView.
This study introduces a novel application of MITRA devices for collecting capillary blood to quantify dexmedetomidine using a newly developed and validated LC–MS/MS method. The highly sensitive developed method was successfully applied to analyze patient whole blood samples.
Lorena Lucatello, Martina Franzin, Gabriele Stocco, Jenny Bua, Francesca Cossovel, Riccardo Addobbati, Francesca Capolongo   +6 more
wiley   +1 more source