Results 11 to 20 of about 97,224 (305)
An Update on the Synthesis of Pyrrolo[1,4]benzodiazepines
Pyrrolo[1,4]benzodiazepines are tricyclic compounds that are considered “privileged structures” since they possess a wide range of biological activities.
George Varvounis
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Introduction: Benzodiazepines are commonly prescribed but often misused, leading to dependence and withdrawal symptoms. Increased worldwide prescriptions raise adverse effects and overdose concerns, especially for the elderly.
Agnė Okulevičiūtė +1 more
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Objective Benzodiazepines were excluded from Medicare Part D coverage since its introduction in 2006. Part D expanded coverage for benzodiazepines in 2013.
Minghui Li +3 more
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Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis
Background & Aims: Benzodiazepines are associated with an increased risk of harm in patients with cirrhosis. However, stopping benzodiazepines must be done with care to avoid withdrawal or other unintended consequences. The impact of deprescribing on
Elliot B. Tapper +3 more
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Pattern of utilization of benzodiazepines in patients with hypertension: A pilot study [PDF]
Background/Aim. The analysis of drug prescribing in general practice in Serbia showed that the use of benzodiazepines is most frequently associated with hypertension.
Divac Nevena +7 more
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Benzodiazepines: Their Use either as Essential Medicines or as Toxics Substances
This review highlights the nature, characteristics, properties, pharmacological differences between different types of benzodiazepines, the mechanism of action in the central nervous system, and the degradation of benzodiazepines. In the end, the efforts
Edilma Sanabria +3 more
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Experiences with benzodiazepine use, tapering, and discontinuation: an Internet survey
Background: Over 92 million prescriptions for benzodiazepines are dispensed in the United States annually, yet little is known about the experiences of those taking and discontinuing them.
Alistair J. Reid Finlayson +4 more
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Synthesis of Substituted 2,3-Benzodiazepines
A new, four-step synthetic route for substituted 2,3-benzodiazepines 1, starting from aldehyde 4, was developed with excellent overall yields. This route included the 1,2-addition of various aromatic Grignard reagents to 4, PCC oxidation, and aerobic ...
Meng-Yang Chang (1393948) +3 more
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Assessing the revised Clinical Institute Withdrawal for Alcohol Scale use at Stikland Hospital
Background: Alcohol use disorder (AUD) is a major public health concern in South Africa (SA). Abrupt cessation or reduction of alcohol intake in chronic users can result in withdrawal symptoms.
Creeshen P. Muddapah, Lize Weich
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