Results 11 to 20 of about 95,300 (255)
Benzodiazepine prescribing behaviour and attitudes: a survey among general practitioners practicing in northern Thailand [PDF]
BMC Family Practice, 2005 Background Over-prescribing of benzodiazepines appears common in many countries, a better understanding of prescribing practices and attitudes may help develop strategies to reduce prescribing.
Critchley Julia +3 more
doaj +3 more sources
Synthesis of Substituted 2,3-Benzodiazepines
, 2016 A new, four-step synthetic route for substituted 2,3-benzodiazepines 1, starting from aldehyde 4, was developed with excellent overall yields. This route included the 1,2-addition of various aromatic Grignard reagents to 4, PCC oxidation, and aerobic ...
Meng-Yang Chang (1393948) +3 more
core +3 more sources
Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]
, 2014 The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
O'Gorman, Paul A +11 more
core +1 more source
Is there a way to curb benzodiazepine addiction?
Swiss Medical Weekly, 2011 Benzodiazepines are widely prescribed drugs used to treat anxiety and insomnia, induce muscle relaxation, control epileptic seizures, promote anaesthesia or produce amnesia. Benzodiazepines are also abused for recreational purposes and the number of
AL Lalive, U Rudolph, C Lüscher, KR Tan
doaj +1 more source
Management of alcohol withdrawal state in a patient with respiratory depression
Kerala Journal of Psychiatry, 2023 Alcohol withdrawal state is generally managed using benzodiazepines. In various studies, it was found that anticonvulsants, including oxcarbazepine, are as effective as benzodiazepines in managing alcohol withdrawal state. This case report highlights the
Arathy Nathan +3 more
doaj +1 more source
Hypnotics and injuries among older adults with Parkinson’s disease: a nested case–control design
BMC Geriatrics, 2023 Background Patients with Parkinson’s disease often experience sleep disorders. Hypnotics increase the risk of adverse events, such as injuries due to falls.
Takako Fujita +4 more
doaj +1 more source
European Psychiatry, 2023 Introduction Benzodiazepines are the most widely prescribed drugs worldwide for insomnia and anxiety disorders. However, few studies have been conducted on the professional practice of these drugs for patients with psychiatric disorders .
S. Brahim +7 more
doaj +1 more source
The Use of Benzodiazepines in the Elderly Population: Epidemiology, Risks and Withdrawal Management [PDF]
Eurasian Journal of Family MedicineBenzodiazepines remain one of the most commonly prescribed medications. Approximately 9% of adults in the United States aged 65 years or above are benzodiazepine users.
Zuzanna Hertz, Szymon Barczak
doaj +1 more source
Angewandte Chemie, EarlyView.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Frontiers in Pharmacology, 2018 Background: Benzodiazepines are driving-impairing medicines (DIM). This study presents current consumption of dispensed benzodiazepines in the Spanish general population, with a focus in pattern of use and concomitant medicines consumed with.Methods: A ...
Francisco Herrera-Gómez +5 more
doaj +1 more source