Results 31 to 40 of about 158,750 (352)

Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research

open access: yesDrugs in R&D, 2017
Various adverse events resulting from, or associated with, benzodiazepine and/or Z-drug use have been extensively reported on and discussed in great detail within the biomedical literature.
Jaden Brandt, Christine Leong
semanticscholar   +1 more source

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines

open access: yes, 2014
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
O'Gorman, Paul A   +11 more
core   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study

open access: yesFrontiers in Pharmacology, 2018
Background: Benzodiazepines are driving-impairing medicines (DIM). This study presents current consumption of dispensed benzodiazepines in the Spanish general population, with a focus in pattern of use and concomitant medicines consumed with.Methods: A ...
Francisco Herrera-Gómez   +5 more
doaj   +1 more source

Drugs increase the risk of suicide in the elderly

open access: yesJournal of Education, Health and Sport, 2022
The purpose of this paper is a systematic review of articles and research in the context of drugs used and suicide in elderly patients. Suicide in the elderly may be much more frequent than in the younger population.
Kornelia Kędziora-Kornatowska   +6 more
doaj   +1 more source

Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil

open access: yesCase Reports in Critical Care, 2016
We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease.
Zarah Jordahn   +3 more
doaj   +1 more source

Combining opioids and benzodiazepines: effects on mortality and severe adverse respiratory events.

open access: yesAnnals of Palliative Medicine, 2019
Opioids and benzodiazepines are increasingly used alone or in combination. However, the combined use of these agents increases the risk for potentially lethal respiratory depression.
M. Boon   +3 more
semanticscholar   +1 more source

BENZODIAZEPINES AND DEVELOPMENT OF DELIRIUM IN CRITICALLY ILL CHILDREN: ESTIMATING THE CAUSAL EFFECT

open access: yesCritical Care Medicine, 2018
Objectives: Benzodiazepine use may be associated with delirium in critically ill children. However, benzodiazepines remain the first-line sedative choice in PICUs.
K. Mody   +6 more
semanticscholar   +1 more source

Degradation of 17 Benzodiazepines by the UV/H2O2 Treatment

open access: yesFrontiers in Environmental Science, 2021
Benzodiazepines are one group of psychoactive drugs widely detected in water environments, and their persistence during conventional wastewater treatment has raised great concerns. Here we investigated the degradation of 17 benzodiazepines in water by UV/
Wen-Dan You   +13 more
doaj   +1 more source

Effects of Clonidine versus Midazolam premedication on postoperative pain in patients undergoing elective spinal neurosurgery. Prospective randomized study [PDF]

open access: yesRomanian Journal of Medical Practice, 2017
Many preoperative, intraoperative and postoperative interventions and management strategies are available and continue to evolve for reducing and managing postoperative pain.
Ana-Maria Cotae   +6 more
doaj   +1 more source

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