Results 41 to 50 of about 158,750 (352)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

The Characteristics of Benzodiazepine Prescribing in the Republic of Srpska, Bosnia and Herzegovina

Medicina, 2022
Background and Objectives: Benzodiazepines (BZDs) are among the most prescribed psychotropic drugs and significant number of patients use these drugs for longer periods than recommended. The objective of this study was to determine the factors associated
Žana M. Maksimović, Mladen Stajić, Miloš P. Stojiljković, Svjetlana Stoisavljević Šatara, Nataša Stojaković, Ranko Škrbić   +5 more
doaj   +1 more source

Non-medical prescribers and benzodiazepines: A qualitative study

, 2014
Benzodiazepines continue to be widely prescribed in primary care for longer than guidelines advise and can cause adverse consequences for those who have long-term prescriptions.
Brodie, Liz, Donaldson, Jayne, Watt, Susan   +2 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

An Update on the Synthesis of Pyrrolo[1,4]benzodiazepines

Molecules, 2016
Pyrrolo[1,4]benzodiazepines are tricyclic compounds that are considered “privileged structures” since they possess a wide range of biological activities.
George Varvounis
doaj   +1 more source

Case report on antipsychotic induced catatonia in an incarcerated patient

Frontiers in Psychiatry, 2023
Antipsychotic-induced catatonia is an iatrogenic and debilitating adverse reaction, but there is a dearth of recent documented cases. This report describes a 35-year-old incarcerated Korean-American male with a history of unspecified psychosis who ...
Han Nguyen, Ruslana Cannell, Suman Rollakanti, Johanna Rosenthal, Johanna Rosenthal, David Seigler, David Seigler   +6 more
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Prediction of Drug–Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation

Drugs in R&D, 2019
Background Researchers have long been interested in the potential drug–drug interactions (DDIs) between opioids and benzodiazepines. However, much remains unknown concerning the interactions between these two drug classes.
Beihong Ji, Shuhan Liu, Ying Xue, Xibing He, Viet Hoang Man, Xiang-Qun Xie, Junmei Wang   +6 more
doaj   +1 more source

Validation of the Patient Health Questionnaire‐2 (PHQ‐2) in Detecting Depression Among Older Adults

AGING MEDICINE, EarlyView.
PHQ‐2 effectively screens for geriatric depression with the optimal cut‐off of 3 points. ABSTRACT Objectives Depression screening tools like the Patient Health Questionnaire‐2 (PHQ‐2) are commonly used to detect depression. However, its performance in elderly populations has been less extensively studied compared to its broader adult use.
Francesco Salis, Maristella Belfiori, Alessandro Ferrau, Eleonora Bernardini, Emanuele Concas, Anna Maria Lugas, Antonella Mandas   +6 more
wiley   +1 more source

Social Listening of Benzodiazepines Abuse and Misuse

Emerging Trends in Drugs, Addictions, and Health
Introduction: Benzodiazepines are Class C drugs that can act as anxiolytics, hypnotics, sedatives, and muscle relaxants. Over the decade, benzodiazepine misuse has proliferated with increasing numbers of newly emerging benzodiazepines.
A. Guirguis
doaj   +1 more source