Results 61 to 70 of about 73,532 (265)
Epileptic Disorders, EarlyView.Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori +4 more
wiley +1 more source
Ciência Rural, 1995 Na presente pesquisa avaliou-se a associação flunitrazepam/droperidol na tranqüilização/sedação de 12 suínos da raça Landrace. Os animais foram divididos em dois grupos (GI e GII).
José António Marques +3 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden +5 more
wiley +1 more source
Long-Term Insomnia Treatment with Benzodiazepines and Alzheimer’s Disease: A Systematic Review
NeuroSciAlzheimer’s disease is the most common form of dementia. Benzodiazepines are the most widely used pharmacological class in the treatment of insomnia and other sleep disorders. Some literature suggests that the chronic use of benzodiazepines is associated
Filipa Sofia Trigo +2 more
doaj +1 more source
Journal of the Formosan Medical Association, 2015 The aim of this study was to examine the correlations between the severity of alprazolam dependence and socio-demographic characteristics, the characteristics of alprazolam use, psychiatric comorbidity, and beliefs toward alprazolam use among long-term ...
Tzu-Ting Chen +7 more
doaj +1 more source
Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats
Epilepsia, EarlyView.Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire +7 more
wiley +1 more source
Benzodiazepines and risk of dementia – Is there a reason for alarm?
European PsychiatryIntroduction The population ageing is a reality associated with an increase in prevalence of Dementia. The use of benzodiazepines is often postulated as a risk factor in these syndromes.
R. P. L. Andrade +8 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal +47 more
wiley +1 more source