Results 311 to 320 of about 146,798 (343)
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Neuroscience & Biobehavioral Reviews, 1985
This article sets the background for the following series of articles on the behavioral actions of drugs acting at the GABA-benzodiazepine receptor complex. The articles provide detailed analyses of particular behaviors and emphasise the danger of interpreting all behavioral effects in terms of anxiety.
Steven J. Cooper, Sandra E. File
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This article sets the background for the following series of articles on the behavioral actions of drugs acting at the GABA-benzodiazepine receptor complex. The articles provide detailed analyses of particular behaviors and emphasise the danger of interpreting all behavioral effects in terms of anxiety.
Steven J. Cooper, Sandra E. File
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Clinical Obstetrics & Gynecology, 2019
Benzodiazepine use and dependence are on the rise as well as the number of deaths attributable to the combination of opioids and benzodiazepines. Anxiety, the most frequent condition for which benzodiazepines are prescribed, occurs commonly, and is increasingly noted to coincide with pregnancy.
Shaweta Babbar +3 more
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Benzodiazepine use and dependence are on the rise as well as the number of deaths attributable to the combination of opioids and benzodiazepines. Anxiety, the most frequent condition for which benzodiazepines are prescribed, occurs commonly, and is increasingly noted to coincide with pregnancy.
Shaweta Babbar +3 more
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Journal of Psychiatric Research, 1990
The frequency and quantity of alcohol consumption is a major consideration in patients who need treatment with benzodiazepines. Alcohol affects the GABA-benzodiazepine-chloride ionophore complex and has an agonist-like action. Thus, additive interactions should be expected from combining alcohol with benzodiazepines. Furthermore, alcohol has clinically
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The frequency and quantity of alcohol consumption is a major consideration in patients who need treatment with benzodiazepines. Alcohol affects the GABA-benzodiazepine-chloride ionophore complex and has an agonist-like action. Thus, additive interactions should be expected from combining alcohol with benzodiazepines. Furthermore, alcohol has clinically
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Benzodiazepine and Non-Benzodiazepine Anxiolitics
Psychopathology, 1984A review of anxiolytic drugs is presented, including ethyl alcohol, barbiturates, diphenylmethane derivatives, glycerol and propanediol derivatives, antipsychotics, and antidepressants. Focus on the benzodiazepines and their metabolism and method of action follows.
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ChemInform Abstract: AN OPIOID BENZODIAZEPINE
Chemischer Informationsdienst, 1982AbstractEs wird über pharmakologische Ergebnisse berichtet, die zeigen, daß Tifluadom (KG 5103) (I) ein Vertreter einer neuen Klasse von Benzodiazepinen ist, der keine Affinität zu sonstigen Benzodiazepin‐Rezeptoren besitzt, sondern selektiv an den Opiat‐K‐Rezeptoren wirkt.
R. Maurer +9 more
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Advances in Alcohol & Substance Abuse, 1990
The benzodiazepines were first introduced in 1960. Chlordiazepoxide (Librium) was the first of the class of drugs called benzodiazepines, in a deliberate attempt to synthesize a tranquilizer without the sedative properties and abuse, addiction, tolerance, and dependence potential of the barbiturates, and other sedative/hypnotic drugs. The popularity of
N S, Miller, M S, Gold
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The benzodiazepines were first introduced in 1960. Chlordiazepoxide (Librium) was the first of the class of drugs called benzodiazepines, in a deliberate attempt to synthesize a tranquilizer without the sedative properties and abuse, addiction, tolerance, and dependence potential of the barbiturates, and other sedative/hypnotic drugs. The popularity of
N S, Miller, M S, Gold
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Treatment of Benzodiazepine Dependence
New England Journal of Medicine, 2017Long-term use of benzodiazepines can lead to dependence. Symptoms of withdrawal include anxiety, irritability, confusion, seizures, and sleep disorders. Withdrawal management relies on the use of a single agent (diazepam) and gradual dose reduction.
LUGOBONI, FABIO +2 more
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Benzodiazepines in Schizophrenia
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996Benzodiazepines have a checkered history in the United States; public and professional attitudes about them have ranged from their being wonder drugs in the 1970s to being virtually purged from many formularies as addictive and dangerous in the 1980s. The attitude today is that they are useful for specific indications.
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The Damnation of Benzodiazepines
British Journal of Psychiatry, 1989It is argued that there are two kinds of benzodiazepine dependence: a therapeutic and a morbid kind. The therapeutic dependence is acceptable in that it mitigates the clinical manifestations in patients with long-standing and fluctuating anxious–depressive symptoms.
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The History of Benzodiazepines
The Consultant Pharmacist, 2013After more than 50 years of experience with benzodiazepines, the American health care system has a love-hate relationship with them. In 1955, Hoffmann-La Roche chemist Leo Sternbach serendipitously identified the first benzodiazepine, chlordiazepoxide (Librium).
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