Results 11 to 20 of about 1,710 (123)

2-(1,3-Benzodioxol-5-yl)-1H-benzimidazole [PDF]

Acta Crystallographica Section E Structure Reports Online, 2014
The asymmetric unit of the title compound, C14H10N2O2, contains two independent molecules. In each molecule, the benzodioxole ring system displays an envelope conformation, with the methylene C atom located at the flap deviating by 0.081 (2) and 0.230 (2) Å from the mean plane formed by the other atoms.
Nadir Ghichi, Mohamed Amine Benaouida, Ali Benosmane, Ali Benboudiaf, Hocine Mérazig   +4 more
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1,3-Benzodioxol-2-one

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C7H4O3, is the first cyclic carbonate of an aromatic diol whose structure has been elucidated by means of single-crystal X-ray analysis. The mol­ecule possesses crystallographic twofold rotation symmetry and non-crystallographic C2v symmetry. The C—O single bonds are slightly longer than those in comparable cyclic carbonates derived
Richard Betz, Peter Klüfers
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1-(1,3-Benzodioxol-5-yl)pentan-1-one [PDF]

Acta Crystallographica Section E Structure Reports Online, 2008
In the mol-ecule of title compound, C(12)H(14)O(3), the benzodioxole ring system is essentially planar. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link mol-ecules into chains along the c axis, and π-π contacts between dioxole rings and between dioxole and benzene rings of the benzodioxole ring systems [centroid-centroid ...
Xiao-Ming Wang, Wei Cheng, Yu-Wang Han
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1,2-Bis[(1,3-benzodioxol-5-yl)methylidene]hydrazine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The complete mol-ecule of the title compound, C(16)H(12)N(2)O(4), is generated by the application of a centre of inversion. The (1,3-benzodioxol-5-yl)methyl-idene fused-ring system is approximately planar (r.m.s. deviation = 0.020 Å) and is essentially coplanar with the central hydrazine group [dihedral angle = 5.08 (9)°].
Jasinski, Jerry P., Golen, James A., Praveen, A. S., Narayana, B., Yathirajan, H. S.   +4 more
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2,2-Bis(pentafluorophenyloxy)-1,3-benzodioxole

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C19H4F10O4, an orthocarbonate of a vicincal aromatic diol and two monofunctional aromatic alcohols, was prepared for the purpose of collecting NMR data on orthocarbonates and for comparison with similar silicon compounds. The mol­ecule does not exhibit any crystallographic symmetry.
Richard Betz, Peter Klüfers, Moritz M. Reichvilser   +2 more
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Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts

European Journal of Organic Chemistry, EarlyView.
A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha, Gabriel G. Rocha, Fábio M. F. Santos, Stefan Bräse, M. Manuel B. Marques   +4 more
wiley   +1 more source

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

Plant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Ebru Koçak Aslan, Kevin Lam, Sun Huang, Göknil Pelin Coşkun, Ayşe Karagüzel, Katrin Denzinger, Kaan Birgül, Mert Ülgen, Jordan W. Nafie, Onur Şahin, Daniel W. Armstrong, Gerald W. Zamponi, Gerhard Wolber, Miyase Gözde Gündüz   +13 more
wiley   +1 more source

2-(2H-1,3-Benzodioxol-5-yl)-1,3-benzothiazole [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title compound, C14H9O2S, the benzothiazole unit is oriented at a dihedral angle of 7.1 (1)° with respect to the benzodioxole unit. The dioxole ring adopts flattened envelope conformation with the methylene C atom at the flap. The crystal packing is stabilized by π–π interactions [centroid–centroid distances = 3.705 (1) and 3.752 (1) Å], C—H...π
D. Lakshmanan, S. Murugavel, R. Selvakumar, M. Bakthadoss   +3 more
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