Results 71 to 80 of about 17,221 (205)
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Paul Besrukow +3 more
wiley +1 more source
A series of five new 2‐(1‐benzofuran‐2‐yl)‐2‐oxoethyl 4-(un/substituted)benzoates 4(a–e), with the general formula of C8H5O(C=O)CH2O(C=O)C6H4X, X = H, Cl, CH3, OCH3 or NO2, was synthesized in high purity and good yield under mild conditions.
C. S. Chidan Kumar +9 more
doaj +1 more source
A Pd/Cu cooperative catalytic system enables the direct C–H functionalization of a diverse range of five‐membered and benzo‐fused heterocycles with iodinated hexaarylborazines, providing efficient access to previously inaccessible heterocycle‐functionalized borazines.
Fan Huang +5 more
wiley +1 more source
Three‐component thio‐ and carbo‐boration reactions to form functionalised benzoxaborinines and benzazaborinines are reported. The nucleophile scope includes thioethers, thiols, and (hetero)arenes. Mechanistic studies revealed a disparity between thioboration using thioethers and using thiols.
Laura Winfrey +4 more
wiley +2 more sources
Background/Objectives: DNA-targeting small molecules that induce replication stress represent a promising strategy in anticancer drug development.
Zlatina Vlahova +9 more
doaj +1 more source
An efficient cascade cyclization strategy was developed to synthesize aminobenzofuran spiroindanone and spirobarbituric acid derivatives utilizing 2-bromo-1,3-indandione, 5-bromo-1,3-dimethylbarbituric acid, and ortho-hydroxy α-aminosulfones as ...
Rong-Rong Zhu, Xi-Qiang Hou, Da-Ming Du
doaj +1 more source
An “on‐water” scalable Pd‐catalyzed heteroannulation delivers benzofurans and furopyridines at ultralow catalyst loadings (down to 0.005 mol%), providing products essentially free of palladium residues. In addition to a broad substrate scope (aryl, alkenyl, and alkyl alkynes with o‐iodophenols or 2‐iodo‐3‐hydroxypyridines), this protocol enables a new ...
Iratxe Astarloa +3 more
wiley +1 more source
Unlocking Stereodefined Olefins by Z‐Selective Transition Metals‐catalyzed C−H Activations
The synthesis of Z‐olefins is an important challenge in synthetic organic chemistry. Within this review, we report a comprehensive overview of transition metals‐catalyzed Z‐selective C–H activations of (hetero)arenes for the synthesis of stereodefined olefins.
Francesco Capranica +2 more
wiley +1 more source
Under copper(I) catalysis, pentafluoroethylated alkenes can undergo smooth defluorosilylation to generate novel polyfluorinated products. The reaction exhibits high levels of diastereoselectivities for obtaining multisubstituted allylsilanes with control of the double bond geometry.
Yuwei Zong, Yihan Tang, Gavin Chit Tsui
wiley +1 more source
The ever-increasing spread of bacterial infection with rising antibacterial drug resistance has become a matter of global concern in the modern times. Therefore, such serious infections leading to high mortality rate has necessitated the search for new ...
Bhushan Nazirkar +2 more
doaj +1 more source

