Results 81 to 90 of about 17,790 (155)

Chemical Constituents of the Deep‐Sea‐Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
One new tyramine derivative (1) and 28 known compounds (2–29) were isolated from deep‐sea‐derived fungus Talaromyces wortmannii. Their structures were elucidated by NMR/MS and computational calculations. Compounds 2 and 6 potently inhibited ferroptosis with EC5₀ values of 4.52 and 13.73 µM.
Ke‐Xin Ma, Zheng‐Biao Zou, Qi‐Qian Wu, Li‐Sheng Li, Ying‐Ni Pan, Xian‐Wen Yang   +5 more
wiley   +1 more source

Overview of Photochemical Reactions for the Synthesis of Aza and Oxa‐Spirocyclic Compounds Under Visible Light Irradiation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj, Shivangi Jaiswal, Khushboo Bhardwaj, Swapnil Sharma, Jaya Dwivedi   +4 more
wiley   +1 more source

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Temperature‐Controlled Diene Cyclization Toward Trifluoromethyl Biphenyl Derivatives: Synthetic and Computational Study

ChemCatChem, Volume 18, Issue 18, 28 September 2026.
Synthesis of functionalized polyfluorinated biphenyl moieties via one‐pot Heck coupling followed by temperature‐controlled cyclization reaction of polyfluoro diene intermediate. The cyclization reaction proceeds via a palladium‐catalyzed β‐fluoro elimination step.
Bálint Varga, Khaled T. Jaradat, Martin Polyák, János Kele‐Jókuthy, Attila Herczegh, András Kotschy, Zoltán Novák, János Daru   +7 more
wiley   +1 more source

Thermal decomposition kinetics of benzofuran derived polymer/organosilicate nanocomposites

Kuwait Journal of Science, 2016
Benzofuran derived polymer poly(2-(5-bromo benzofuran-2-yl)-2-oxoethylmethacrylate)/organically modified montmorillonite nanocomposites were preparedvia in situ polymerization technique.
Adnan Kurt, Pınar Yilmaz
doaj  

Piptadenia gonoacantha Leaf Extracts: Seasonal and Phenological Effects on Chemical Profile, Antioxidant and Photoprotective Potential

ChemistrySelect, Volume 11, Issue 36, 22 September 2026.
The front cover image demonstrates how seasonal environmental factors influence the phenolic composition and bioactivity of Piptadenia gonoacantha leaves. The visual elements represent ultrasound‐assisted extraction and chromatographic separation, while the light and natural images reflect how solar radiation and phenological stage directly influence ...
Nicole Werle da Silva, Maria Luiza de Vargas Mallmann, Lucas Mironuk Frescura, Gustavo Andrade Ugalde, Camilo Amaro de Carvalho, Marcelo Barcellos da Rosa   +5 more
wiley   +1 more source

(E)-1-(1-(Benzofuran-2-yl)ethylidene)-2-(2,4,6-trichlorophenyl)hydrazine

Molbank
The reaction of a mixture of equimolar quantities of 2-acetylbenzofuran and (2,4,6-trichlorophenyl)hydrazine in ethanol containing concentrated hydrochloric acid (0.2 mL; 37%) as a catalyst under reflux for two hours yielded 1-(1-(benzofuran-2-yl ...
Bakr F. Abdel-Wahab, Hanan A. Mohamed, Benson M. Kariuki, Gamal A. El-Hiti   +3 more
doaj   +1 more source

Discovery of ERα‐Targeting Phytochemicals With In Vitro Cytotoxicity and Computational Prediction of Y537S Mutant Inhibition

Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
Integrating high‐throughput virtual screening, cytotoxicity assays, and molecular dynamics simulations, this study identifies the phytochemical ibs‐04156 as a reliable dual‐action candidate across both wild‐type and mutated estrogen receptor alpha (ERα), while ibs‐18821 emerges as a potent allosteric inhibitor specifically targeting the drug‐resistant ...
Dejun Jiang, Oh Wook Kwon, Hanbin Joe, Euijeong Shin, Sungjoon Cho, Hyuk‐Ku Kwon, Youngjin Choi   +6 more
wiley   +1 more source

Synthesis and Biological Activity of 2,6‐Disubstituted and 2,6,9‐Trisubstituted 7‐Deazapurine Nucleobases

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Four series of 20 (het)aryl substituted 7‐deazapurine nucleobases were synthesized. Several potent antagonists of all four subtypes of adenosine receptors were identified by functional assay. High‐throughput screening of the IMTM compound library for modulatory activity on adenosine receptors (ARs) identified two deazapurine hits based on 2,6‐diaryl‐7 ...
Ugnė Šinkevičiūtė, Kateřina Burgetová Ječmeňová, Soňa Gurská, Lenka Poštová Slavětínská, Vincent Baran, Pavel Polishchuk, Petr Džubák, Michal Hocek, Marián Hajdúch, Michal Tichý   +9 more
wiley   +1 more source

Novel benzofuran-furan-pyrano[2,3-<i>c</i>]pyrazole hybrids as potential anticancer agents: design, synthesis, <i>in silico</i> profiling, and multi-mechanistic biological evaluation. [PDF]

RSC Adv
Hutanu ED, Najri BA, Abdelsalam AH, Saidi KM, Arslan S, Kivrak A.   +5 more
europepmc   +1 more source