Results 81 to 90 of about 30,744 (240)
Climate change‐driven expansion of goosegrass highlights risks to global food production
Climate change is expanding the climatic suitability of Eleusine indica into temperate agricultural regions, increasing its overlap with major soybean and maize production areas. These findings highlight a growing global threat to food security and the need for proactive weed management strategies.
Thiago Deomar Ludwig +4 more
wiley +1 more source
One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra +8 more
wiley +2 more sources
Starting from benzofuran-2-methanal, 6-substituted benzothiazole-2-amines and malonic esters, sixteen title compounds were designed and synthesized seeking to introduce anti-TMV activity.
Meichuan Li +8 more
doaj +1 more source
A Simple Approach to Distinguish Classic and Formaldehyde-Free Tannin Based Rigid Foams by ATR FT-IR [PDF]
Tannin based rigid foams (TBRFs) have been produced with formaldehyde since 1994. Only recently several methods have been developed in order to produce these foams without using formaldehyde.
Alexander, Petutschnigg +3 more
core +1 more source
Metal‐Free Electrophilic Borylative Cyclizations of Alkynes
Metal‐free borylative cyclizations based on electrophilic alkyne activation by boron Lewis acids provide efficient access to borylated hetero‐ and carbocycles. Early studies using B(C6F5)3 displayed limited scope and application, whereas recent ClBcat‐ and BCl3‐based methods enable mild CB and CC/CX bond formation for the synthesis of cycles ...
Jaime Mateos‐Gil +3 more
wiley +1 more source
Crystal structure of 5-fluoro-2-(3-fluorophenyl)-3-methylsulfinyl-1-benzofuran
In the title compound, C15H10F2O2S, the dihedral angle between the planes of the benzofuran ring system [r.m.s. deviation = 0.015 (1) Å] and the 3-fluorophenyl ring is 26.60 (5)°. In the crystal, molecules are linked by C—H...O and C—H...F hydrogen bonds,
Hong Dae Choi, Uk Lee
doaj +1 more source
Enantioselective Biotransformation of Prochiral Ketone via Daucus carota [PDF]
Biotransformations of prochiral ketones can be performed using plant cells. The benefits of using plant cells include low cost, environmentally sound procedures compared to conventional chemical processes, and the stereospecific nature of the reaction.1 ...
Davis, Elizabeth +2 more
core +1 more source
Organocatalytic Vinyl and Friedel−Crafts Alkylations with Trifluoroborate Salts [PDF]
Herein we report the first use of vinyl and heteroaryl trifluoroborate salts as viable substrates for amine-catalyzed conjugate additions. The application of LUMO-lowering iminium catalysis has enabled the highly regio- and enantioselective 1,4-addition ...
Lee, Sandra, MacMillan, David W. C.
core +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
A fragment-based drug discovery approach was taken to target the thiol-disulfide oxidoreductase enzyme DsbA from Escherichia coli (EcDsbA). This enzyme is critical for the correct folding of virulence factors in many pathogenic Gram-negative bacteria ...
Luke F. Duncan +5 more
doaj +1 more source

