Results 181 to 190 of about 8,390 (243)

Nickel-catalyzed cross-coupling of 2-fluorobenzofurans with arylboronic acids via aromatic C-F bond activation. [PDF]

Beilstein J Org Chem
Fujita T, Yabuki H, Morioka R, Fuchibe K, Ichikawa J.   +4 more
europepmc   +1 more source

NCS-Mediated <i>Ipso</i>-Halogenation of Arylboronic Acids in Water Using Sodium Halides. [PDF]

ACS Omega
Santarsiere A, Galgano P, Funicello M, Lupattelli P, Chiummiento L.   +4 more
europepmc   +1 more source

Mild Photochemical Reduction of Alkenes and Heterocycles via Thiol-Mediated Formate Activation. [PDF]

Org Lett
Brzezinski CU, LeBlanc AR, Clerici MG, Wuest WM.   +3 more
europepmc   +1 more source

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Synthesis of polyfluorinated benzofurans

Journal of Fluorine Chemistry, 2019
Abstract A simple and efficient approach to the synthesis of fluorinated benzofurans including the Sonogashira cross-coupling of o-iodophenols with terminal Ph- and n-Bu-acetylenes, followed by intramolecular cyclization, in good to excellent yields is reported.
Larisa Politanskaya, E V Tretyakov, Chanjuan Xi   +2 more
exaly   +2 more sources

Regioselective Synthesis of Benzofuranones and Benzofurans

The Journal of Organic Chemistry, 2021
Reaction of 3-hydroxy-2-pyrones with nitroalkenes bearing ester groups gives benzofuranones. The reaction allows regioselective preparation of the benzofuranones with programmable substitution at any position. Complex substitution patterns are readily created. The substituted benzofuranones can be converted to substituted benzofurans.
Xiaojie Zhang, Christopher M. Beaudry
openaire   +2 more sources

Benzofuran derivatives. Part 3 On the reactivities of the intermediates in benzofuran synthesis

Journal of Heterocyclic Chemistry, 1987
Abstract3‐Methyl‐5‐nitrobenzofuran (2) and 3‐methyl‐5‐nitrobenzofuran‐2‐carboxylic acid (3) were obtained by heating 2‐acetyl‐4‐nitrophenoxyacetic acid (1) with various bases in acetic anhydride. It appeared that 3‐hydroxy‐3‐methyl‐5‐nitro‐2,3‐dihydrobenzofuran‐2‐carboxylic acid (4) was the intermediate in the benzofuran synthesis.
Takaaki Horaguchi, Shinichi Matsuda, Kiyoshi Tanemura, Tsuneo Suzuki   +3 more
openaire   +1 more source

Bioactive Benzofuran derivatives: A review

European Journal of Medicinal Chemistry, 2015
In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a major group. The broad spectrum of pharmacological activity in individual benzofurans indicates that this series of compounds is of an undoubted interest.
Hena, Khanam, , Shamsuzzaman
openaire   +2 more sources

Biological and medicinal significance of benzofuran

European Journal of Medicinal Chemistry, 2015
This article emphasizes on the importance of benzofuran as a biologically relevant heterocycle. It covers most of the physiologically as well as medicinally important compounds containing benzofuran rings. This article also covers clinically approved drugs containing benzofuran scaffold.
Nevagi, Reshma J., Dighe, Santosh N., Dighe, Satish N.   +2 more
openaire   +5 more sources

Benzofuran based PDE4 inhibitors

Bioorganic & Medicinal Chemistry, 1999
Replacement of the 3,4-dialkoxyphenyl substructure common to a number of PDE4 inhibitors with a 2-alkyl-7-methoxybenzofuran unit is described. This substitution can result in either enhancement or substantial reductions in PDE4 inhibitory activity depending on the system to which it is applied.
D G, McGarry, J R, Regan, F A, Volz, C, Hulme, K J, Moriarty, S W, Djuric, J E, Souness, B E, Miller, J J, Travis, D M, Sweeney   +9 more
openaire   +2 more sources