Results 141 to 150 of about 16,649 (384)

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin‐10 Antagonism

open access: yesArthritis &Rheumatology, EarlyView.
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes   +14 more
wiley   +1 more source

Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective We aimed to evaluate the influence of contrast‐enhanced dual‐energy computed tomography (CE‐DECT) in detecting and differentiating rheumatic joint diseases of the hand. Methods In this prospective study, patients with suspected arthritis of the hand were investigated consecutively alongside the standard clinical procedure.
Sevtap Tugce Ulas   +9 more
wiley   +1 more source

American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel

open access: yesArthritis &Rheumatology, EarlyView.
Objective Vacuoles E1 enzyme X‐linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.
Arsene M. Mekinian   +111 more
wiley   +1 more source

Epidermal Interferon kappa drives cutaneous lupus‐like lesions, photosensitivity and systemic autoimmunity in vivo

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein   +14 more
wiley   +1 more source

Sex Ratio and Success, an Assessment of Lindera melissifolia in Arkansas [PDF]

open access: yes, 1994
Lindera melissifolia pondberry, is a federally endangered dioecious shrub found in Arkansas and four other southeastern states. Although by far the greatest area exists in Arkansas, it is broken into numerous small single-sex clones concentrated in two ...
Wright, Robert D.
core   +1 more source

Development of a Donor−Acceptor Concept for Enzymatic Cross-Coupling Reactions of Aldehydes: The First Asymmetric Cross-Benzoin Condensation [PDF]

open access: green, 2002
Pascal Dünkelmann   +8 more
openalex   +1 more source

Semantic primitives and compositionality: An Annual Review of Information Science and Technology (ARIST) paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract The term semantic primitives refers to a set of basic, atomic concepts from which all other (compound) concepts are constructed. It presupposes the principle of compositionality—the idea that complex items or expressions can be formed by combining simpler constituents.
Birger Hjørland
wiley   +1 more source

Lindera benzoin Blume

open access: yes, 2007
Laurus benzoin Linnaeus, Species Plantarum 1: 370. 1753. "Habitat in Virginia." RCN: 2920. Lectotype (Fernald in Rhodora 47: 141, pl. 889. 1945): Herb. Clifford: 154, Laurus 2 (BM-000558697). Current name: Lindera benzoin (L.) Blume (Lauraceae).
openaire   +2 more sources

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