Results 171 to 180 of about 16,998 (233)

Organocatalytic Synthesis of Chiral Benzopyrans.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thavendran Govender, Leila Hojabri, Firouz Matloubi Moghaddam, Per I. Arvidsson   +3 more
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New benzopyrans: Anticonvulsant activities

Life Sciences, 1975
Three new analogs of dimethylheptylpyran (DMHP) (SP-141, SP-143, and SP-175) were found to exhibit significant anticonvulsant activity against audiogenic, supramaximal electroshock, and maximal pentylentetrazol induced seizures in mice. In rats, all three compounds were found to be more active than diphenylhydantoin in the supramaximal electroshock ...
N P, Plotnikoff, H E, Zaugg, A C, Petersen, D L, Arendsen, R F, Anderson   +4 more
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Benzopyrans from Hypericum polyanthemum

Phytochemistry, 2001
From the aerial parts of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferae), three chromenes, 6-isobutyryl-5,7-dimethoxy-2,2-dimethyl-benzopyran; 7-hydroxy-6-isobutyryl-5-methoxy-2,2-dimethyl-benzopyran and 5-hydroxy-6-isobutyryl-7-methoxy-2,2-dimethyl-benzopyran were isolated. Their structures were determined by NMR spectroscopic analyses.
A B, Ferraz, S A, Bordignon, C, Staats, J, Schripsema, G L, Lino von Poser   +4 more
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Sulfamic Acid: An Efficient Catalyst for the Diastereoselective, One-Pot Synthesis of Pyrano Benzopyrans, Furano Benzopyrans and Ethoxy Benzopyrans

Letters in Organic Chemistry, 2005
Sulfamic acid catalyses the one-pot three components coupling of aldehydes, anilines and electron rich dienophiles such as dihydropyran, dihydrofuran and ethyl vinylether resulting in the formation of pyrano, furano and ethoxy benzopyrans.
R. Kumar, R. Nagarajan, K. Vijay, P. Perumal   +3 more
openaire   +1 more source

Antimicrobial Benzopyrans from the Receptacle of Sunflower

Bioscience, Biotechnology, and Biochemistry, 1996
The antimicrobial substances in sunflower (Helianthus annuus) were investigated. Two antifungal benzopyran derivatives, 6-acetyl-2,2-dimethyl-1,2-benzopyran (1) and 6-acetyl-7-hydroxy-2,2-dimethyl-1,2-benzopyran (2), were isolated from the ethanol extract of sunflower receptacles.
A, Satoh, H, Utamura, M, Ishizuka, N, Endo, M, Tsuji, H, Nishimura   +5 more
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A New Efficient Synthesis of Spirocyclic Benzopyrans

Synthesis, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Gregoire Pave, Pierre Chalard, Marie‐Claude Viaud‐Massuard, Yves Troin, Gerald Guillaumet   +4 more
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A benzopyran derivative substituted at position 3

Acta Crystallographica Section C Crystal Structure Communications, 2002
In (E)-3-[[(diphenoxyphosphoryl)methylhydrazono]methyl]-4H-1-benzopyran-4-one, C(23)H(19)N(2)O(5)P, the benzopyran-methylhydrazone moiety is planar and the two phenoxy phenyl rings are inclined at angles of 21.29 (6) and 89.33 (5) degrees. Weak C[bond]H...O and C[bond]H...N intramolecular interactions exert some influence on the planarity and ...
Agnieszka J, Rybarczyk-Pirek, Magdalena, Małecka, Sławomir J, Grabowski S, Jolanta, Nawrot-Modranka   +3 more
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Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring

Bioorganic & Medicinal Chemistry Letters, 2007
Benzopyrans are selective estrogen receptor (ER) beta agonists (SERBAs), which bind the ER receptor subtypes alpha and beta in opposite orientations. We have used structure based drug design to show that this unique phenomena can be exploited via substitution at the 8-position of the benzopyran A-ring to disrupt binding to ERalpha, thus improving ...
Bryan H, Norman, Timothy I, Richardson, Jeffrey A, Dodge, Lance A, Pfeifer, Gregory L, Durst, Yong, Wang, Jim D, Durbin, Venkatesh, Krishnan, Sean R, Dinn, Shengquan, Liu, John E, Reilly, Kendal T, Ryter   +11 more
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Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators

Bioorganic & Medicinal Chemistry, 2019
We describe the synthesis of 26 compounds, small polycerasoidol analogs, that are Lipinski's rule-of-five compliant. In order to confirm key structural features to activate PPARα and/or PPARγ, we have adopted structural modifications in the following parts: (i) the benzopyran core (hydrophobic nucleus) by benzopyran-4-one, dihydrobenzopyran or ...
Bermejo, Almudena, Barrachina, Isabel, El Aouad, Noureddine, Franck, Xavier, Chahboune, Nadia, Andreu, Inmaculada, Figadère, Bruno, Vila, Laura, Hennuyer, Nathalie, Staels, Bart, Dacquet, Catherine, Caignard, Daniel, Sanz, María-Jesús, Cortes, Diego, Cabedo, Nuria   +14 more
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Benzopyrans. Part 23. Nitrogen heterocycles fused with or linked to 1-benzopyran from 3-acyl-2-methyl-1-benzopyran-4-one

Journal of the Chemical Society, Perkin Transactions 1, 1988
The enamine (2), prepared from the title benzopyranone (1; R2= H, Me, and Ph) and dimethylformamide dimethyl acetal, on treatment with ammonia and hydroxylamine gives the fused pyridine (5) and pyridine 2-oxide (10), respectively. Hydrazine, phenylhydrazine, and guanidine undergo initial 1,6-addition to the enamine (2) ultimately giving the pyrazoles ...
Chandra Kanta Ghosh, Chandana Pal, Jharna Maiti, Manjusha Sarkar   +3 more
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