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BENZOPYRAN: A BIOLOGICALLY ACTIVE SCAFFOLD
International Journal of Biology, Pharmacy and Allied Sciencesopenaire +1 more source
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New benzopyrans: Anticonvulsant activities
Life Sciences, 1975Three new analogs of dimethylheptylpyran (DMHP) (SP-141, SP-143, and SP-175) were found to exhibit significant anticonvulsant activity against audiogenic, supramaximal electroshock, and maximal pentylentetrazol induced seizures in mice. In rats, all three compounds were found to be more active than diphenylhydantoin in the supramaximal electroshock ...
N P, Plotnikoff +4 more
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Benzopyrans from Hypericum polyanthemum
Phytochemistry, 2001From the aerial parts of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferae), three chromenes, 6-isobutyryl-5,7-dimethoxy-2,2-dimethyl-benzopyran; 7-hydroxy-6-isobutyryl-5-methoxy-2,2-dimethyl-benzopyran and 5-hydroxy-6-isobutyryl-7-methoxy-2,2-dimethyl-benzopyran were isolated. Their structures were determined by NMR spectroscopic analyses.
A B, Ferraz +4 more
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Benzopyran derivatives from Mallotus apelta
Phytochemistry, 2001From the leaves of Mallotus apelta, seven benzopyran compounds were obtained and their structures were determined using spectroscopic methods. One showed moderate antibiotic activity against Micrococcus lutens.
T Y, An, L H, Hu, X F, Cheng, Z L, Chen
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Organocatalytic Synthesis of Chiral Benzopyrans.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thavendran Govender +3 more
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Letters in Organic Chemistry, 2005
Sulfamic acid catalyses the one-pot three components coupling of aldehydes, anilines and electron rich dienophiles such as dihydropyran, dihydrofuran and ethyl vinylether resulting in the formation of pyrano, furano and ethoxy benzopyrans.
R. Kumar +3 more
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Sulfamic acid catalyses the one-pot three components coupling of aldehydes, anilines and electron rich dienophiles such as dihydropyran, dihydrofuran and ethyl vinylether resulting in the formation of pyrano, furano and ethoxy benzopyrans.
R. Kumar +3 more
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Journal of the Chemical Society, Chemical Communications, 1983
Trapping and low temperature matrix isolation experiments show that 2-benzopyran-3-one (1) is efficiently generated by thermolysis or photolysis of the bis-lactone (2); flash vacuum thermolysis of (2) yields isocoumarin (5) and photolysis of (2) in an argon matrix gives (1) and the ketene (6).
David A. Bleasdale +3 more
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Trapping and low temperature matrix isolation experiments show that 2-benzopyran-3-one (1) is efficiently generated by thermolysis or photolysis of the bis-lactone (2); flash vacuum thermolysis of (2) yields isocoumarin (5) and photolysis of (2) in an argon matrix gives (1) and the ketene (6).
David A. Bleasdale +3 more
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Benzopyrans. Part 44. Synthesis of 3‐(4‐Oxo‐4H‐1‐benzopyran‐2‐yl)indolizines.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Chandra Kanta Ghosh +2 more
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Journal of the Chemical Society, Perkin Transactions 1, 1988
The enamine (2), prepared from the title benzopyranone (1; R2= H, Me, and Ph) and dimethylformamide dimethyl acetal, on treatment with ammonia and hydroxylamine gives the fused pyridine (5) and pyridine 2-oxide (10), respectively. Hydrazine, phenylhydrazine, and guanidine undergo initial 1,6-addition to the enamine (2) ultimately giving the pyrazoles ...
Chandra Kanta Ghosh +3 more
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The enamine (2), prepared from the title benzopyranone (1; R2= H, Me, and Ph) and dimethylformamide dimethyl acetal, on treatment with ammonia and hydroxylamine gives the fused pyridine (5) and pyridine 2-oxide (10), respectively. Hydrazine, phenylhydrazine, and guanidine undergo initial 1,6-addition to the enamine (2) ultimately giving the pyrazoles ...
Chandra Kanta Ghosh +3 more
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Benzopyrans from Melicope ptelefolia leaves
Phytochemistry, 1997Abstract Investigation of leaves of Melicope ptelefolia afforded 18 2,2-dimethyl-2H-1-benzopyrans, consisting of 14 new members, including one benzodipyran and four known compounds. Their structures were established by mass and NMR spectroscopy, especially NOE and HMBC experiments. © 1997 Elsevier Science Ltd.
Christine Kamperdick +3 more
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