Results 11 to 20 of about 10,026 (250)

Aluminum triflate catalyzed tandem reactions of D-galactal: toward chiral benzopyrans, chromenes, and chromans.

Organic Letters, 2014
© 2014 American Chemical Society. 3,4,6-Tri-O-acetyl-d-galactal is selectively converted into 1-O-aryl-2-deoxy derivatives or chiral bridged benzopyrans under Al(OTf)3 catalysis, depending on reaction conditions.
Sandile B. Simelane, Henok H. Kinfe, A. Muller, D. Williams   +3 more
semanticscholar   +2 more sources

Antifeedant Activity of Benzopyrans from Melicope latifolia [PDF]

, 2020
Two benzopyrans, evodionol (1), and evodion (2) were isolated from the stem bark of Melicope latifolia. The structure of both compounds was identified based on 1D and 2D NMR, UV, and IR spectroscopy.
Tanjung, Mulyadi
core   +1 more source

Alkaloid and benzopyran compounds of Melicope latifolia fruit exhibit anti-hepatitis C virus activities

BMC Complementary Medicine and Therapies, 2021
Background New agents for developing alternative or complementary medicine to treat the hepatitis C virus (HCV) are still needed due to high rates of HCV infection globally and the current limitations of available treatments.
Aty Widyawaruyanti, Mulyadi Tanjung, Adita Ayu Permanasari, Ratih Saputri, Lidya Tumewu, Myrna Adianti, Chie Aoki-Utsubo, Hak Hotta, Achmad Fuad Hafid, Tutik Sri Wahyuni   +9 more
doaj   +1 more source

Sustainable synthesis of benzopyran derivatives catalyzed by MgO nanoparticles: Spectral, DFT and TEM analysis

Results in Chemistry, 2023
In current work, a magnesium oxide nanocatalyst was synthesized via greener route using aloe-vera plant leaf extracts as a reducing and stabilizing agent to construct MgO nanoparticle.
Har Lal Singh, Mamta Chahar, Sangeeta, Saloni Sahal, Sarita Khaturia   +4 more
doaj   +1 more source

An overview of structure-based activity outcomes of pyran derivatives against Alzheimer’s disease

Saudi Pharmaceutical Journal, 2023
Pyran is a heterocyclic group containing oxygen that possesses a variety of pharmacological effects. Pyran is also one of the most prevalent structural subunits in natural products, such as xanthones, coumarins, flavonoids, benzopyrans, etc. Additionally
Faisal A. Almalki
doaj   +1 more source

Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety.

Journal of Medicinal Chemistry, 2019
σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and ...
Elisabeth Kronenberg, Frauke Weber, S. Brune, D. Schepmann, C. Almansa, Kristina Friedland, E. Laurini, S. Pricl, B. Wünsch   +8 more
semanticscholar   +1 more source

Synthesis of novel photochromic pyrans via palladium-mediated reactions

Beilstein Journal of Organic Chemistry, 2009
Photochromic pyrans for applications in material and life sciences were synthesized via palladium-mediated cyanation, carbonylation and Sonogashira cross-coupling starting from bromo-substituted naphthopyran 1 and benzopyrans 2a/b.
Christoph Böttcher, Gehad Zeyat, Saleh A. Ahmed, Elisabeth Irran, Thorben Cordes, Cord Elsner, Wolfgang Zinth, Karola Rueck-Braun   +7 more
doaj   +1 more source

Quantitative Structure–Activity Relationships of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents

Molecules, 2021
On the basis of the finding that various aminoalkyl-substituted chromene and chromane derivatives possess strong and highly selective in vitro bioactivity against Plasmodium falciparum, the pathogen responsible for tropical malaria, we performed a ...
Friederike M. Wunsch, Bernhard Wünsch, Freddy A. Bernal, Thomas J. Schmidt   +3 more
doaj   +1 more source

Tricyclic flavonoids with 1,3-dithiolium substructure

Beilstein Journal of Organic Chemistry, 2012
The synthesis of new 3-dithiocarbamic flavonoids has been accomplished by the reaction of the corresponding 2-hydroxyaryl dithiocarbamates with aminals. These flavonoids were obtained as a mixture of diastereoisomers, the anti isomer being the major one.
Lucian G. Bahrin, Peter G. Jones, Henning Hopf   +2 more
doaj   +1 more source

Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Scientific Reports, 2018
Successive rounds of chemical modification in three generations of benzopyran molecules have shown to select for different mechanisms of actions and progressive increases in anti-cancer activity.
Alexander J. Stevenson, E. Ager, M. Proctor, D. Škalamera, A. Heaton, David A. Brown, B. Gabrielli   +6 more
semanticscholar   +1 more source