Results 21 to 30 of about 2,171 (174)

Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity

Nature Communications, 2018
Estrogen receptor alpha (ERα) plays critical roles in the etiology and treatment of breast cancer. Here the authors synthesize benzopyrans with variable side chains to identify antiestrogenic compounds and characterize OP-1074, a compound that exhibits ...
S. W. Fanning, L. Hodges-Gallagher, D. C. Myles, R. Sun, C. E. Fowler, I. N. Plant, B. D. Green, C. L. Harmon, G. L. Greene, P. J. Kushner   +9 more
doaj   +1 more source

Amberlyst 15 Catalyzed Prenylation of Phenols: One-Step Synthesis of Benzopyrans

Molecules, 1997
A convenient one-step synthesis of 2,2-dimethylchromans and chromenes using Amberlyst 15 as a catalyst is described.
A. Banerji, A. Jain, G. P. Kalena
doaj   +1 more source

Phenolic Constituents of Flowers

Natural Product Communications, 2008
Species of Hypericum accumulate phenolic compounds with the phloroglucinol substitution pattern, and there are many reports of such substances isolated from the aerial parts of the plants.
Carolina Nör, Ana Paula Machado Bernardi, Juliana Schulte Haas, Jan Schripsema, Sandra Beatriz Rech, Gilsane Lino Von Poser   +5 more
doaj   +1 more source

Essential Oils of Yellow Leaves Obtained by Hydrodistillation and Supercritical Carbon Dioxide Extraction

Natural Product Communications, 2023
Background/Objective: Volatile compounds present in green Ginkgo biloba L. leaves extracts contain compounds that can undertake free radical scavenging.
Nina Djapic
doaj   +1 more source

Synthesis and Evaluation of Thiochroman-4-One Derivatives as Potential Leishmanicidal Agents

Molecules, 2017
The S-containing heterocyclic compounds benzothiopyrans or thiochromones stand out as having promising biological activities due to their structural relationship with chromones (benzopyrans), which are widely known as privileged scaffolds in medicinal ...
Esteban Vargas, Fernando Echeverri, Iván D. Vélez, Sara M. Robledo, Wiston Quiñones   +4 more
doaj   +1 more source

Highly enantioselective access to cannabinoid-type tricyles by organocatalytic Diels–Alder reactions

Beilstein Journal of Organic Chemistry, 2012
After prosperous domino reactions towards benzopyrans, the products were used as the starting material in Lewis acid catalyzed and organocatalytic Diels–Alder reactions to build up a tricyclic system.
Stefan Bräse, Nicole Volz, Franziska Gläser, Martin Nieger   +3 more
doaj   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones

Antioxidants
The antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa, Laura Gabriela Sarbu   +1 more
doaj   +1 more source

Optimising the Eco‐Friendly Extraction of Carotenoids From Gac Fruit: A Sustainable Solution for Natural Red Food Colourants

Food Chemistry International, EarlyView.
Gac fruit's high carotenoid content, especially in the aril, makes it an excellent natural red pigment source for food applications, offering a safer alternative to synthetic dyes. Ethanol extraction achieved the highest overall pigment recovery (89.53%), whereas ethyl lactate extraction yielded the highest levels of total carotenoids, β‐carotene ...
N. Netravati, S. Gomez, B. Pathrose, A. Suma, J. Hosamani   +4 more
wiley   +1 more source

Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments

Marine Drugs, 2013
The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng, Xue-Gong Li, Jun Xu, Tie-Sheng Han, Shu-Jie Xie, Min-Juan Xu, Ya-Hui Wang, Zhi-Gang Zhang, Zhong-Yuan You   +8 more
doaj   +1 more source