Results 31 to 40 of about 3,681 (218)

Oxo-aglaiastatin-mediated inhibition of translation initiation [PDF]

, 2019
We thank Dr. Elias George (McGill University) for the kind gift of Pgp-1-expressing HeLa cells. RIM was supported by a doctoral fellowship from the Cole Foundation.
Brown, Lauren E., Cencic, Regina, Chu, Jennifer, Devine, William G., Maiga, Rayelle Itoua, Pelletier, Jerry, Porco, John A., Sebag, Michael, Waller, Daniel D., Zhang, Wenhan   +9 more
core   +2 more sources

Comparative Metabolomics Study of Four Kinds of Xihu Longjing Tea Based on Machine Fixing and Manual Fixing Methods

Foods, 2023
China Xihu Longjing tea is famous for its good flavor and quality. However, information on its related metabolites, except for flavonoids, is largely deficient. Different processing methods for China Xihu Longjing tea fixing—by machines at both the first
Hongchun Cui, Yuxiao Mao, Yun Zhao, Haitao Huang, Junfeng Yin, Jizhong Yu, Jianyong Zhang   +6 more
doaj   +1 more source

Iodine-Substituted Dithiocarbamic Flavanones—A Structure–Activity Relationship Study of Their Antioxidant Properties

Molecules
The antioxidant properties of novel diiodo-substituted 3-dithiocarbamic flavanones were investigated. The three frameworks that proved to be the most active ones in our previous studies were selected.
Mihail Lucian Birsa, Laura Gabriela Sarbu   +1 more
doaj   +1 more source

Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity

Nature Communications, 2018
Estrogen receptor alpha (ERα) plays critical roles in the etiology and treatment of breast cancer. Here the authors synthesize benzopyrans with variable side chains to identify antiestrogenic compounds and characterize OP-1074, a compound that exhibits ...
S. W. Fanning, L. Hodges-Gallagher, D. C. Myles, R. Sun, C. E. Fowler, I. N. Plant, B. D. Green, C. L. Harmon, G. L. Greene, P. J. Kushner   +9 more
doaj   +1 more source

Amberlyst 15 Catalyzed Prenylation of Phenols: One-Step Synthesis of Benzopyrans

Molecules, 1997
A convenient one-step synthesis of 2,2-dimethylchromans and chromenes using Amberlyst 15 as a catalyst is described.
A. Banerji, A. Jain, G. P. Kalena
doaj   +1 more source

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]

, 2018
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A., Frick, Karyn M., Hanson, Alicia M., Imhoff, Andrea, Kim, Jaekyoon, Lu, Xingyun, Mackinnon, Alexander Craig, Pandey, Rajesh K., Perera, K. L. Iresha Sampathi, Sem, Daniel S., Sweeney, Noreena, Van Hart, Rochelle M., Wargolet, Adam J.   +12 more
core   +4 more sources

A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones

Antioxidants
The antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa, Laura Gabriela Sarbu   +1 more
doaj   +1 more source

Phenolic Constituents of Flowers

Natural Product Communications, 2008
Species of Hypericum accumulate phenolic compounds with the phloroglucinol substitution pattern, and there are many reports of such substances isolated from the aerial parts of the plants.
Carolina Nör, Ana Paula Machado Bernardi, Juliana Schulte Haas, Jan Schripsema, Sandra Beatriz Rech, Gilsane Lino Von Poser   +5 more
doaj   +1 more source

Essential Oils of Yellow Leaves Obtained by Hydrodistillation and Supercritical Carbon Dioxide Extraction

Natural Product Communications, 2023
Background/Objective: Volatile compounds present in green Ginkgo biloba L. leaves extracts contain compounds that can undertake free radical scavenging.
Nina Djapic
doaj   +1 more source

Finding Characteristic Substructures for Metabolite Classes [PDF]

, 2012
We introduce a method for finding a characteristic substructure for a set of molecular structures. Different from common approaches, such as computing the maximum common subgraph, the resulting substructure does not have to be contained in its exact form
Böcker, S., Elshamy, S., Hufsky, F., Ludwig, M.   +3 more
core   +2 more sources