Results 31 to 40 of about 3,645 (198)

Synthesis and Evaluation of Thiochroman-4-One Derivatives as Potential Leishmanicidal Agents

Molecules, 2017
The S-containing heterocyclic compounds benzothiopyrans or thiochromones stand out as having promising biological activities due to their structural relationship with chromones (benzopyrans), which are widely known as privileged scaffolds in medicinal ...
Esteban Vargas, Fernando Echeverri, Iván D. Vélez, Sara M. Robledo, Wiston Quiñones   +4 more
doaj   +1 more source

Iodine-Substituted Dithiocarbamic Flavanones—A Structure–Activity Relationship Study of Their Antioxidant Properties

Molecules
The antioxidant properties of novel diiodo-substituted 3-dithiocarbamic flavanones were investigated. The three frameworks that proved to be the most active ones in our previous studies were selected.
Mihail Lucian Birsa, Laura Gabriela Sarbu   +1 more
doaj   +1 more source

Litter Quality of Populus Species as Affected by Free-Air CO2 [PDF]

, 2009
The effect of elevated CO2 and nitrogen fertilization on the molecular chemistry of litter of three Populus species and associated soil organic matter (SOM) was investigated by pyrolysis-gas chromatography/mass spectrometry.
Buurman, P., Hoosbeek, M.R., Vermue, E.
core   +4 more sources

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Highly enantioselective access to cannabinoid-type tricyles by organocatalytic Diels–Alder reactions

Beilstein Journal of Organic Chemistry, 2012
After prosperous domino reactions towards benzopyrans, the products were used as the starting material in Lewis acid catalyzed and organocatalytic Diels–Alder reactions to build up a tricyclic system.
Stefan Bräse, Nicole Volz, Franziska Gläser, Martin Nieger   +3 more
doaj   +1 more source

Metabolic signatures of triatomine vectors of Trypanosoma cruzi unveiled by metabolomics. [PDF]

PLoS ONE, 2013
Chagas disease is a trypanosomiasis whose causative agent is the protozoan parasite Trypanosoma cruzi, which is transmitted to humans by hematophagous insects known as triatomines and affects a large proportion of South America.
Luis Caetano M Antunes, Jun Han, Jingxi Pan, Carlos J C Moreira, Patrícia Azambuja, Christoph H Borchers, Nicolas Carels   +6 more
doaj   +1 more source

Synthesis and photochromic behaviour of new methyl induced linear and angular thieno-2H-chromenes [PDF]

, 2003
New methyl induced linear and angular thieno-2H-chromenes 4, 5 and 6 were prepared by reaction of new methylated 6-hydroxybenzo[b]thiophenes 2 (a, b and c) and propargylic alcohols 3a and 3b, using acidic Alumina Brockmann I as catalyst and drying agent.
Aubard, Jean, Dubest, Roger, Guglielmetti, Robert J., Plasencia, Paula M. S., Queiroz, Maria João R. P.   +4 more
core   +1 more source

A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones

Antioxidants
The antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa, Laura Gabriela Sarbu   +1 more
doaj   +1 more source

Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments

Marine Drugs, 2013
The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng, Xue-Gong Li, Jun Xu, Tie-Sheng Han, Shu-Jie Xie, Min-Juan Xu, Ya-Hui Wang, Zhi-Gang Zhang, Zhong-Yuan You   +8 more
doaj   +1 more source

Phenolics: from chemistry to biology [PDF]

, 2009
In recent years, few classes of natural products have received as much attention as phenolics and polyphenols. This special issue of Molecules, “Phenolics and Polyphenolics”, is a remarkable confirmation of this trend.
Andrade, P.B., Pereira, D.M., Pereira, J.A., Valentão, P.   +3 more
core   +1 more source