Results 21 to 30 of about 1,330 (160)

Senescence in Intervertebral Disc Degeneration: A Comprehensive Analysis Based on Bioinformatic Strategies

open access: yesImmunity, Inflammation and Disease, Volume 12, Issue 11, November 2024.
Our research performed a comprehensive analysis of senescence‐associated genes (SAGs) in intervertebral disc degeneration, which revealed their functions and expression pattern in intervertebral disc tissue. We identified four hub SAGs, and established a predictive nomogram and explored the potential drugs. Our reserch provide new understandings of SAG
Zijun Zhao   +5 more
wiley   +1 more source

A Novel tsRNA, m7G‐3′ tiRNA LysTTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation

open access: yesAdvanced Science, Volume 11, Issue 31, August 21, 2024.
In this study, it specifically shows that the novel m7G‐modified tRNA‐derived small RNA (tsRNA) m7G‐3′‐tiRNA LysTTT (mtiRL), catalyzed by the tRNA m7G‐modifying enzyme mettl1, specifically binds ANXA2, promoting its Tyr24 phosphorylation, by enhancing ANXA2–Yes1 interactions, leading to ANXA2 activation in bladder cancer (BC) cells and promotes BC ...
Xiaoling Ying   +13 more
wiley   +1 more source

Metal–Organic Frameworks in Surface Enhanced Raman Spectroscopy–Based Analysis of Volatile Organic Compounds

open access: yesAdvanced Science, Volume 11, Issue 30, August 14, 2024.
The integration of Metal–Organic Frameworks (MOF) into Surface‐Enhanced Raman Spectroscopy (SERS) sensors is discussed, focusing on the complex interplay of both worlds, and elucidating respective design rules for maximizing the analytical performance of the platform.
Juan A. Allegretto, Jakub Dostalek
wiley   +1 more source

Interplay between altered metabolism and DNA damage and repair in ovarian cancer

open access: yesBioEssays, Volume 46, Issue 8, August 2024.
The crosstalk between reprogrammed metabolism and DNA repair pathways impacts ovarian cancer in multiple ways, including therapeutic outcomes. Exploiting metabolic pathways to alter DNA repair may provide new targeted therapies to use in combination with standard‐of‐care DNA damaging agents.
Apoorva Uboveja, Katherine M. Aird
wiley   +1 more source

Associations between paediatric obesity, chemical mixtures and environmental factors, in a national cross‐sectional study of Canadian children

open access: yesPediatric Obesity, Volume 19, Issue 8, August 2024.
Summary Background Whilst single chemical exposures are suspected to be obesogenic, the combined role of chemical mixtures in paediatric obesity is not well understood. Objectives We aimed to evaluate the potential associations between chemical mixtures and obesity in a population‐based sample of Canadian children.
Rose Dugandzic   +12 more
wiley   +1 more source

Significance of lignin and fungal markers in the Devonian (407 Ma) Rhynie Chert

open access: yesGeobiology, Volume 22, Issue 4, July/August 2024.
Abstract The Rhynie Chert (Lower Devonian, Scotland) hosts a remarkably well‐preserved early terrestrial ecosystem. Organisms including plants, fungi, arthropods, and bacteria were rapidly silicified due to inundation by silica‐rich hot spring fluids.
Alex I. Holman   +10 more
wiley   +1 more source

Humanistic Health Management and Cancer: Associations of Psychology, Nutrition, and Exercise with Cancer Progression and Pathogenesis

open access: yesAdvanced Science, Volume 11, Issue 22, June 12, 2024.
The occurrence of cancer is directly related to personal life habits. Through self‐health management, cancer can be effectively prevented and treated. Therefore, the concept of humanistic health management is put forward, which is a new personalized and comprehensive cancer prevention and control program involving individual psychological conditions ...
Chenchen Li   +10 more
wiley   +1 more source

Combustion Completeness and Sample Location Determine Wildfire Ash Leachate Chemistry

open access: yesGeochemistry, Geophysics, Geosystems, Volume 25, Issue 5, May 2024.
Abstract Understanding past fire regimes and how they vary with climate, human activity, and vegetation patterns is fundamental to the mitigation and management of changing fire regimes as anthropogenic climate change progresses. Ash‐derived trace elements and pyrogenic biomarkers from speleothems have recently been shown to record past fire activity ...
Micheline Campbell   +7 more
wiley   +1 more source

Ketogenic Diet Slows Down Weight Gain in Juvenile Mus musculus with Benzopyrene as Cancer Inducer

open access: bronze, 2021
Dita Mega Utami   +5 more
openalex   +2 more sources

Home - About - Disclaimer - Privacy