Results 51 to 60 of about 26,979 (280)

Electrochemical oxidation of benzoic acid and its aromatic intermediates on boron doped diamond electrodes

open access: yesCurrent Research in Green and Sustainable Chemistry, 2021
Electrochemical oxidation using Boron-doped diamond (BDD) electrodes is a promising purification technique to remove organic pollutants, such as benzoic acid, from wastewaters. In this study the oxidation of benzoic acid has been investigated on rotating
Anke Arts   +3 more
doaj   +1 more source

Enhanced Photocatalytic H2O2 Production on Terpyridine‐Based Acrylonitrile‐Linked Covalent Organic Frameworks with Asymmetric Localized Electron Distribution

open access: yesAdvanced Materials, EarlyView.
Asymmetric localized electron distribution has been optimized in covalent organic frameworks to enhance *O2 adsorption and facilitate charge transfer, boosting photocatalytic two‐electron transfer oxygen reduction toward H2O2 production from water and air.
Qinglan Zhao   +12 more
wiley   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

open access: yesAdvanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu   +7 more
wiley   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane   +4 more
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

open access: yesAdvanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

Synthesis of Some Mono-, Bis- NH-substituted-1,4-Benzoquinones

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2018
The preparation of new mono- and bis- NH-substituted-1,4-benzoquinones, namely 2,5-bis(5,6-dimethylbenzo[d]thiazol-2-ylamino)cyclohexa-2,5-diene-1,4-dione (3), 2,5-bis(3-(2-methylpiperidin-1-yl)propylamino)-3-chlorocyclohexa-2,5-diene-1,4-dione (6), 2-(4-
Ayşecik Kaçmaz
doaj   +1 more source

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang   +15 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

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