Results 71 to 80 of about 26,979 (280)

First Characterization of a Cyanobacterial Xi-Class Glutathione S-Transferase in Synechocystis PCC 6803

Antioxidants
Glutathione S-transferases (GSTs) are evolutionarily conserved enzymes crucial for cell detoxication. They are viewed as having evolved in cyanobacteria, the ancient photosynthetic prokaryotes that colonize our planet and play a crucial role for its ...
Fanny Marceau, Marlène Lamothe-Sibold, Sandrine Farci, Soufian Ouchane, Corinne Cassier-Chauvat, Franck Chauvat   +5 more
doaj   +1 more source

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

Mechanisms of interaction of acetaminophen metabolites in terms of hepatotoxicity

Current Issues in Pharmacy and Medical Sciences, 2013
The most serious complication after ingestion of a toxic dose of acetaminophen is liver damage. The aim of study was to review the research on the biochemical and molecular mechanisms of acetaminophen hepatotoxicity.
Milena Topoła, Magdalena Podawacz, Mariola Śliwińska-Mossoń, Waldemar Sajewicz, Halina Milnerowicz   +4 more
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Scandium Ion-Promoted Photoinduced Electron-Transfer Oxidation of Fullerenes and Derivatives by p-Chloranil and p-Benzoquinone

, 2016
In the presence of scandium triflate, an efficient photoinduced electron transfer from the triplet excited state of C60 to p-chloranil occurs to produce C60 radical cation which has a diagnostic NIR (near-infrared) absorption band at 980 nm, whereas no ...
Osamu Ito (560209), Shunichi Fukuzumi (1326822), Hiroshi Imahori (1270452), Hisahiro Mori (2986920), Yasuyuki Araki (1582255), Karl M. Kadish (1431214), Tomoyoshi Suenobu (1453036)   +6 more
core   +1 more source

Supplm_Data_19-12-2019 – Supplemental material for Regioselective synthesis of new 7,8-dichlorobenzofuro[3,2-c]quinoline-6,9,10(5H)-triones from reactions of 4-hydroxy-2-quinolones with 3,4,5,6-tetrachloro-1,2-benzoquinone

, 2020
Supplemental material, Supplm_Data_19-12-2019 for Regioselective synthesis of new 7,8-dichlorobenzofuro[3,2-c]quinoline-6,9,10(5H)-triones from reactions of 4-hydroxy-2-quinolones with 3,4,5,6-tetrachloro-1,2-benzoquinone by Ashraf A Aly, Alaa A Hassan ...
Ashraf A Aly (6980324), Nasr K Mohamed (8435442), Lamiaa E Abd El-Haleem (8435445), Alaa A Hassan (8435439), Stefan Bräse (2454700)   +4 more
core   +1 more source

Cobalt Single‐Atom Catalysts for Ultrafast Sulfamethoxazole Degradation: Unveiling the Chloride‐Ion‐Enhanced Formation of Co(IV)=O

Advanced Science, EarlyView.
An atomically dispersed Co–N4 single‐atom catalyst rapidly activates peroxymonosulfate to remove the antibiotic sulfamethoxazole from water. Common ions have little impact, but chloride dramatically speeds degradation by promoting a high‐valent Co(IV) = O oxidant via in situ HOCl–catalyst electron transfer.
Anting Ding, Jing Lu, Yafei Fan, Chenyu Zeng, Yuhang Lin, Yufei Shi, Zulin Zhang   +6 more
wiley   +1 more source

Influence of Diene Substitution on Diels−Alder Reactions between Vinyl Dihydronaphthalenes and (SS)-2-(p-Tolylsulfinyl)-1,4-benzoquinone

, 2016
The asymmetric Diels−Alder reaction between 2-(E-2-acetoxyvinyl)-8-tert-butyl-3,4-dihydronaphthalene (8) and enantiopure (SS)-2-(p-tolylsulfinyl)-1,4-benzoquinone (1) takes place exclusively on the unsubstituted C5−C6 double bond of (SS)-1 with a very ...
Susana García-Cerrada (2984943), M. Carmen Carreño (2466826), M. Jesús Sanz-Cuesta (2662348), Antonio Urbano (1447507)   +3 more
core   +1 more source

Synthesis and optoelectronic properties of benzoquinone-based donor–acceptor compounds

Beilstein Journal of Organic Chemistry, 2019
Herein, we report a mild and efficient palladium-catalyzed C–H functionalization method to synthesize a series of benzoquinone (BQ)-based charge-transfer (CT) derivatives in good yields. The optoelectronic properties of these compounds were explored both
Daniel R. Sutherland, Nidhi Sharma, Georgina M. Rosair, Ifor D. W. Samuel, Ai-Lan Lee, Eli Zysman-Colman   +5 more
doaj   +1 more source

Hydrothermal Humification of Biomass for Circular Carbon Management in Sustainable Agro‐Ecosystems

Advanced Science, EarlyView.
This article provides a comprehensive overview of biomass hydrothermal humification for building sustainable agro‐ecosystems. It examines the chemical transformation mechanisms and the functional benefits of the produced humic acids in soil remediation.
Ziyun Liu, Zonglu Yao, Yuanhui Zhang, Huiyan Zhang, Lixin Zhao   +4 more
wiley   +1 more source