Results 11 to 20 of about 17,647 (331)

Border between natural product and drug: Comparison of the related benzoquinones idebenone and coenzyme Q10

open access: goldRedox Biology, 2015
Coenzyme Q10 is a ubiquitous component of cellular membranes and belongs to the class of benzoquinones that mainly differ with regards to the length and composition of their hydrophobic tail.
Nuri Gueven   +2 more
doaj   +2 more sources

Neuroprotective effect and mechanism of idebenone on hippocampal damage induced by epileptic seizure

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To investigate the protective effect of idebenone (IDBN) on hippocampal neuron injury in epileptic rats and its mechanism. Methods Forty-eight Wistar rats were randomly divided into normal control group, IDBN prevention group (prevention group),
QIAO Shan   +5 more
doaj   +1 more source

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Geldanamycin (GDM) has been modified by different type neutral/acidic/basic substituents (1–7) and by quinuclidine motif (8), transformed into ammonium salts (9–13) at C(17).
Natalia Skrzypczak   +8 more
doaj   +1 more source

Effects of Benzoquinones on Radicles of Orobanche and Phelipanche Species

open access: yesPlants, 2021
The holoparasitic broomrape weeds (Orobanche and Phelipanche species) cause severe yield losses throughout North Africa, the Middle East, and Southern and Eastern Europe. These parasitic weeds form an haustorium at the tip of their radicles to infect the
Mónica Fernández-Aparicio   +3 more
doaj   +1 more source

Harvestman Phenols and Benzoquinones: Characterisation and Biosynthetic Pathway

open access: yesMolecules, 2013
Benzoquinones are usually present in arthropod defence exudates. Here, we describe the chemical profiles of 12 harvestman species belonging to the neotropical family Gonyleptidae.
Glauco Machado   +5 more
doaj   +1 more source

Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones [PDF]

open access: yesJournal of the Serbian Chemical Society, 2002
The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated.
SNEZANA TRIFUNOVIC   +5 more
doaj   +3 more sources

Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite [PDF]

open access: yes, 1988
The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described.
Herscheid, Jacobus D.M.   +3 more
core   +3 more sources

Novel Anti-Aging Benzoquinone Derivatives from Onosma bracteatum Wall

open access: yesMolecules, 2019
The aim of this study was to investigate anti-aging molecules from Onosma bracteatum Wall, a traditional medicinal plant used in the Unani and Ayurvedic systems of medicine. During bioassay-guided isolation, two known benzoquinones, allomicrophyllone (1)
Umer Farooq   +3 more
doaj   +1 more source

Metal-Free Aminohalogenation of Quinones With Alkylamines and NXS at Room Temperature

open access: yesFrontiers in Chemistry, 2022
A simple and practical strategy for intermolecular aminohalogenation of quinone with alkyl amines and NXS was developed, in which haloamines generated in situ were employed as bifunctional reagents.
Jia Li, Yu-An Li, Ge Wu, Xu Zhang
doaj   +1 more source

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