Metal-Free Aminohalogenation of Quinones With Alkylamines and NXS at Room Temperature
Frontiers in Chemistry, 2022 A simple and practical strategy for intermolecular aminohalogenation of quinone with alkyl amines and NXS was developed, in which haloamines generated in situ were employed as bifunctional reagents.
Jia Li, Yu-An Li, Ge Wu, Xu Zhang
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Synthesis and cytotoxic activity of geranylmethoxyhydroquinone derivatives [PDF]
, 2012 Indexación: Web of Science; ScieloEl geranilo-2 ,4-sintético nuevo methoxyhydroquinone 1 y el conocido geranilo-4 ,5 methoxyhydroquinone- 2 se prepararon por sustitución electrófila aromática (EAS) reacciones entre geraniol y 1,3,5-trimethoxyphenol ...
Baeza Maturana, Evelyn +5 more
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Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity [PDF]
Toxicology, 2016 Benzoquinone (BQ) and benzoquinone derivatives (BQD) are used in the production of dyes and cosmetics. While BQ, an extreme skin sensitizer, is an electrophile known to covalently modify proteins via Michael Addition (MA) reaction whilst halogen substituted BQD undergo nucleophilic vinylic substitution (SNV) mechanism onto amine and thiol moieties on ...
Wilbes Mbiya +3 more
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Electrochemistry of potentially bioreductive alkylating quinones : Part 1. Electrochemical properties of relatively simple quinones, as model compounds of mitomycin- and aziridinylquinone-type antitumour agents [PDF]
, 1990 The influence of methyl-, hydroxy and amino substituents on the electrochemical behaviour of simple 1,4-naphtho-and 1,4-benzoquinones, model compounds of many quinoid antitumour agents, in aqueous media was studied. Significant changes in electrochemical
Bos, M. +9 more
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Biosynthesis of food constituents: Natural pigments: Part 1
Czech Journal of Food Sciences, 2007 This review article gives a survey of the generally accepted biosynthetic pathways that lead to the most important natural pigments in organisms closely related to foods and feeds.
Jan Velíšek +2 more
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Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs [PDF]
, 2017 Quinone-based compounds have been exploited to treat infectious diseases and cancer, with such chemicals often functioning as inhibitors of key metabolic pathways or as prodrugs.
Alsford, Sam +7 more
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Targeting the substrate preference of a type I nitroreductase to develop antitrypanosomal quinone-based prodrugs. [PDF]
, 2012 Nitroheterocyclic prodrugs are used to treat infections caused by Trypanosoma cruzi and Trypanosoma brucei. A key component in selectivity involves a specific activation step mediated by a protein homologous with type I nitroreductases, enzymes found ...
Alsford +68 more
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Orthoporus fuscipes (PORAT, 1888) (Juliformia; Spirostreptidae): population structure and defensive secretion chemical analysis [PDF]
Anais da Academia Brasileira de CiênciasDiplopods are terrestrial arthropods important for the dynamics of terrestrial ecosystems. One of the reasons for that can be their low predation rate due to their defensive secretion.
JULIA A. ROMÃO +8 more
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Egg Production Constrains Chemical Defenses in a Neotropical Arachnid. [PDF]
PLoS ONE, 2015 Female investment in large eggs increases the demand for fatty acids, which are allocated for yolk production. Since the biosynthetic pathway leading to fatty acids uses the same precursors used in the formation of polyketides, allocation trade-offs are ...
Taís M Nazareth, Glauco Machado
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Mechanistic Studies of the Photoinduced Quinone Trimethyl Lock Decaging Process [PDF]
, 2017 Mechanistic studies of a general reaction that decages a wide range of substrates on exposure to visible light are described. The reaction involves a photochemically initiated reduction of a quinone mediated by an appended thioether.
Dougherty, Dennis A. +3 more
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