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Benzoxazine: A Privileged Scaffold in Medicinal Chemistry

Current Medicinal Chemistry, 2023
Background: Benzoxazine is one of the most important privileged scaffolds in medicinal chemistry. Compounds bearing benzoxazine moiety usually have a variety of biological activities, such as anti-inflammatory, anti-microbial, anti-tuberculosis, anti-oxidant and anti-cancer activities.
Zilong Tang, Yichao Wan
exaly   +3 more sources

Highly active antimycobacterial derivatives of benzoxazine

Bioorganic and Medicinal Chemistry, 2010
New 3-(4-alkylphenyl)-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 3-(4-alkylphenyl)-2H-1,3-benzoxazine-2,4(3H)-dithiones were synthesized. The compounds were tested for in vitro antimycobacterial activity against Mycobacterium tuberculosis, Mycobacterium avium and two strains of Mycobacterium kansasii.
Karel Waisser, Jir̂Í Kunes
exaly   +3 more sources

Benzoxazine Miniemulsions Stabilized with Polymerizable Nonionic Benzoxazine Surfactants

Macromolecules, 2010
For the first time, the concept of polymerizable nonionic benzoxazine surfactants is described. Different target structures with varying hydrophobic−lipophilic balance (HLB) values were synthesized...
Sawaryn, C., Landfester, K., Taden, A.
openaire   +2 more sources

Novel benzoxazines as inhibitors of angiogenesis

Investigational New Drugs, 2014
Dysregulation of angiogenesis has been associated with many pathological disorders, including cancer; where angiogenesis has been found to be critical for the maintenance and metastasis of tumours. One of the pathways involved in the regulation of angiogenesis is the phosphatidylinositol3-kinase (PI3K) signalling pathway.
Sara, Al-Rawi   +3 more
openaire   +2 more sources

Carboxylic acid‐containing benzoxazines as efficient catalysts in the thermal polymerization of benzoxazines

Journal of Polymer Science Part A: Polymer Chemistry, 2008
AbstractThe autocatalytic thermal polymerization behavior of three benzoxazine monomers containing carboxylic acid functionalities is reported. Several mixtures of these carboxylic monomers and 3‐phenyl‐3,4‐dihydro‐2H‐1,3‐benzoxazine were prepared and their thermal polymerization behavior was analyzed by differential scanning calorimetry.
R. Andreu, J. A. Reina, J. C. Ronda
openaire   +1 more source

Chitosan/biological benzoxazine composites: Effect of benzoxazine structure on the properties of composites

Reactive and Functional Polymers, 2021
Abstract In this study, two bio-based benzoxazines, PH-f and SA-f, were synthesized and used to prepare benzoxazine/chitosan (CS) composites of PH-f/CS and SA-f/CS and their corresponding curing products poly(PH-f)/CS and poly(SA-f)/CS. Differential scanning calorimeter (DSC) and Fourier-transform infrared spectroscopy (FTIR) spectra show that ...
Yunhe Yang   +5 more
openaire   +1 more source

Benzoxazine Miniemulsions Stabilized with Multifunctional Main-chain Benzoxazine Protective Colloids

Macromolecules, 2011
The morphology control of thermoset systems is one of the key challenges to obtain high performance materials like structural adhesives or advanced protective coatings.
Sawaryn, C., Landfester, K., Taden, A.
openaire   +2 more sources

Synthesis and antimicrobial activity of new benzofuranyl-1,3-benzoxazines and 1,3-benzoxazin-2-ones

Journal of Heterocyclic Chemistry, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ravi K. Ujjinamatada   +2 more
openaire   +1 more source

RADIOSENSITIZING EFFECTS OF NOVEL BENZOXAZINES

2014
Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Pharmacy and Applied Science, Faculty of Science, Technology and Engineering, La Trobe University, Bendigo.
openaire   +1 more source

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