Results 71 to 80 of about 18,220 (243)

A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

Beilstein Journal of Organic Chemistry, 2010
The development of efficient Friedel–Crafts alkylations of arenes and heteroarenes using only catalytic amounts of a Lewis acid has gained much attention over the last decade.
Magnus Rueping, Boris J. Nachtsheim
doaj   +1 more source

Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation

Angewandte Chemie International Edition, EarlyView.
A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister, Giulia Iannelli, Péter Angyal, Augustin Malandain, Daniel Kaiser, Boris Maryasin, Hanspeter Kählig, Matteo Barel, Gaia Novarino, Nuno Maulide   +9 more
wiley   +1 more source

Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation

Angewandte Chemie International Edition, EarlyView.
An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier, Thomas J. Tiefel, Oliver Reiser   +2 more
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30

EFSA Journal, 2011
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider in this revision 3 of Flavouring Group Evaluation 20, the SCF Opinion on benzoic acid.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Bio-inspired manganese-catalyzed deaminative hydroxylation of benzyl amines to corresponding alcohols

Nature Communications
Direct conversion of amines to corresponding alcohols is challenging even under harsh reaction conditions. Inspired by enzymatic transamination, we present a transamination borrowing-hydrogen strategy that enables the direct and selective Mn-catalyzed ...
Jiale Ji, Shiliang Wang, Zhaowen Dai, Yinghao Huo, Limin Wang, Qingshu Zheng, Tao Tu   +6 more
doaj   +1 more source

Eco-Friendly Homo- and Cross-Etherification of Benzyl Alcohols Catalyzed by Iron(II/III) Chloride in Propylene Carbonate as a Green and Recyclable Solvent. [PDF]

ACS Omega, 2023
Slimi H, Litim Z, Ollevier T, Kraïem J.
europepmc   +1 more source

Boron Lewis Acid Catalysis Enables the Direct Cyanation of Benzyl Alcohols by Means of Isonitrile as Cyanide Source. [PDF]

Molecules, 2023
Xu TT, Zhou JL, Cong GY, Sheng JY, Wang SQ, Ma Y, Feng JJ.   +6 more
europepmc   +1 more source

Aerobic oxidation of benzyl alcohol on zinc oxide-supported gold nanostructures

Nano Express
This study focuses on the development of efficient catalysts for the selective oxidation of alcohols to high-value intermediates, including aldehydes, ketones, and carboxylic acids, which are key components in pharmaceuticals and fragrances.
Anh-Tuan Vu, Thu Trang Nguyen, An Le Thi Hai   +2 more
doaj   +1 more source

Influence of Aliphatic Chain Length on Structural, Thermal and Electrochemical Properties of n-alkylene Benzyl Alcohols: A Study of the Odd-Even Effect. [PDF]

Molecules, 2022
Balić T, Paurević M, Počkaj M, Medvidović-Kosanović M, Goman D, Széchenyi A, Preisz Z, Kunsági-Máté S.   +7 more
europepmc   +1 more source