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Bepotastine besilate for the treatment of perennial allergic rhinitis
Expert Opinion on Pharmacotherapy, 2018Bepotastine besilate (BB) is a second-generation H1-antihistamine that, as an ophthalmic solution, is approved in the United States by the Food and Drug Administration (FDA) for the treatment of allergic conjunctivitis. In other countries, the oral presentation of BB is widely used for the improvement of symptoms of allergic rhinitis (AR) as well as ...
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The purpose of this review is to examine published non-clinical literature on the antihistamine bepotastine besilate, including pharmacokinetic and pharmacologic properties.Standard literature searches using diverse databases were used to find articles on bepotastine besilate published between 1997 and 2009.
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Improved Synthesis of Bepotastine Besilate
Organic Preparations and Procedures International, 2021Bepotastine besilate (1, Figure 1, synonymous with bepotastine besylate), is a non-sedative highly selective histamine receptor antagonist, which has a stabilizing effect on mast cells.
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Pharmacokinetic Comparisons of Bepotastine Besilate and Bepotastine Salicylate in Healthy Subjects
Clinical Drug Investigation, 2013Bepotastine is a second-generation histamine H(1) receptor antagonist that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease. The aim of the present study was to compare the pharmacokinetics of two different bepotastine formulations [bepotastine besilate 10 mg (reference) and bepotastine salicylate 9.64 mg (test)],
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