Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data [PDF]
Frontiers in PharmacologyBackgroundThis study analyzed neuropsychiatric adverse drug events (ADEs) associated with cetirizine and levocetirizine using data from the FDA Adverse Event Reporting System (FAERS) and EudraVigilance databases to inform safer clinical use for different
Tingting Yang +9 more
doaj +2 more sources
Hot-Melt Pneumatic Extrusion-Based 3D-Printed Bilayer Tablets Enabling Sequential Release of Levocetirizine and Montelukast [PDF]
PharmaceuticsBackground/Objectives: This study aimed to develop bilayer tablets using hot-melt pneumatic extrusion (HMPE)-based 3D printing for the integrated treatment of allergic rhinitis and asthma.
Ga-Ram Kim +3 more
doaj +2 more sources
A comprehensive clinical evaluation of levocetirizine in the treatment of chronic urticaria in children [PDF]
Frontiers in PharmacologyObjectiveLevocetirizine is a second-generation antihistamine that is the first-line drug recommended by the guidelines for the treatment of chronic urticaria in children. However, the current study focused mainly on adults, and a comprehensive evaluation
Liu Lu +3 more
doaj +2 more sources
Generalized Bullous Fixed Drug Eruption Secondary to Levocetirizine: A Lesson Learned! [PDF]
Clinical Case ReportsFixed drug eruption (FDE) is a unique type of adverse drug eruption characterized by a well‐defined erythematous to violaceous patch that recurs at the same site upon re‐exposure to causative drugs and resolves with hyperpigmentation.
Mahesh Mathur +4 more
doaj +2 more sources
Is Gender an Important Factor in the Precision Medicine Approach to Levocetirizine?
PharmaceuticsCurrently, there is insufficient information on the variability in levocetirizine pharmacometrics among individuals, a crucial aspect for establishing its clinical use.
Yong-Bok Lee +2 more
exaly +3 more sources
Preparation and Evaluation of Long-Acting Injectable Levocetirizine Prodrug Formulation [PDF]
PharmaceuticsBackground/Objectives: Levocetirizine (LCZ) is a second-generation antihistamine with minimal central nervous system effects. However, its short half-life necessitates daily dosing, potentially reducing adherence in pediatric populations.
Jun-hyun Ahn
doaj +2 more sources
Spectroscopic interaction studies of H2 receptor antagonists with levocetirizine
Pakistan Journal of Pharmaceutical Sciences, 2021 Patients with allergic rhinitis may also suffer abdominal pain, gastritis or peptic ulcer. In this condition patient may use levocetirizine with famotidine or ranitidine. These drugs have potential to interact with another drug and form complex. The aim
Shafaque Mehboob +10 more
doaj +1 more source
A case of levocetirizine-induced liver injury [PDF]
Clinical and Molecular Hepatology, 2016 Levocetirizine is a second-generation nonsedative antihistaminic agent that has been demonstrated to be safe and effective for treating allergic disease.
Moon Chan Jung +7 more
doaj +1 more source
Clinical Dermatology Review, 2023 Background: Management of chronic spontaneous urticaria (CSU) is challenging because of its unpredictable course and negative influence on the quality of life. Second-generation antihistaminics are the first-line treatment. Levocetirizine, a time-tested
Gaurav Menghani +5 more
doaj +1 more source
Clinical Dermatology Review, 2022 Background: Second-generation antihistamines (SGAHs) are first-line drugs in management of chronic spontaneous urticaria (CSU). However, almost 50% of the patients do not respond to standard dose of SGAH.
Bela Shah +6 more
doaj +1 more source