Enhanced Stability and Compatibility of Montelukast and Levocetirizine in a Fixed-Dose Combination Monolayer Tablet [PDF]
The purpose of this study was to enhance the stability of montelukast and levocetirizine for the development of a fixed-dose combination (FDC) monolayer tablet.
Tae Han Yun +4 more
doaj +4 more sources
Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data [PDF]
BackgroundThis study analyzed neuropsychiatric adverse drug events (ADEs) associated with cetirizine and levocetirizine using data from the FDA Adverse Event Reporting System (FAERS) and EudraVigilance databases to inform safer clinical use for different
Tingting Yang +9 more
doaj +2 more sources
The Efficacy of Levocetirizine in Allergic Rhinitis in Children [PDF]
Controversies about the preferred treatment of mild persistent or mild-to-moderate intermittent allergic rhinitis were considered in the study involved 62 primary school childrenю They were randomized to receive oral formulation of levocetirizine (5 mg ...
S.L. Nyankovsky +5 more
doaj +2 more sources
The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect? [PDF]
Levocetirizine, the R-enantiomer of cetirizine dihydrochloride has pharmacodynamically and pharmacokinetically favourable characteristics, including rapid onset of action, high bioavailability, high affinity for and occupancy of the H1-receptor, limited ...
Walsh Garry M
doaj +3 more sources
Immobilization of Levocetirizine on Mesoporous Silica for Antiallergenic Gel Formulation [PDF]
Levocetirizine dihydrochloride is an effective antiallergenic drug applied mostly orally; however, developing a topical formulation for localized treatment could be beneficial.
Klára Szentmihályi +10 more
doaj +2 more sources
Levocetirizine Modulates Lymphocyte Activation in Patients With Allergic Rhinitis [PDF]
Levocetirizine, a second generation non-sedating antihistamine that blocks the H1 histamine receptor, may exhibit immunoregulatory properties that augment its primary pharmacological mechanism.
Fadia Mahmoud +3 more
doaj +2 more sources
Levocetirizine as treatment for symptoms of seasonal allergic rhinitis [PDF]
Levocetirizine as treatment for symptoms of seasonal allergic rhinitis. Objectives: The aim of this study was to assess the effectiveness and safety of levocetirizine in the treatment of the symptoms of seasonal allergic rhinitis (SAR) in patients ...
M. Jorissen +3 more
doaj +3 more sources
The Effectiveness of Levocetirizine in Comparison with Loratadine in Treatment of Allergic Rhinitis —A Meta-Analysis [PDF]
Background: Oral antihistamines are considered the gold standard therapy for allergic rhinitis to date. The goal of this investigation is to make an indirect comparison between loratadine, an oral antihistamine available over-the-counter (OTC) in the USA,
Ralph Mösges +2 more
doaj +2 more sources
Hot-Melt Pneumatic Extrusion-Based 3D-Printed Bilayer Tablets Enabling Sequential Release of Levocetirizine and Montelukast [PDF]
Background/Objectives: This study aimed to develop bilayer tablets using hot-melt pneumatic extrusion (HMPE)-based 3D printing for the integrated treatment of allergic rhinitis and asthma.
Ga-Ram Kim +3 more
doaj +2 more sources
Levocetirizine versus Bilastine as Monotherapy in the Management of Chronic Spontaneous Urticaria: A Randomised Controlled Trial [PDF]
Introduction: Chronic urticaria is defined as the almost daily occurrence of wheals and pruritus for a minimum of six weeks, adversely affecting the quality of life and necessitating management with a drug with better efficacy and a high safety profile ...
Roshini Rajendran +3 more
doaj +3 more sources

