Results 121 to 130 of about 1,103 (154)

A Randomized, Multicenter Phase 3 Clinical Trial Evaluating Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis. [PDF]

Clin Ophthalmol
Kenyon K, McLaurin EB, Silverstein SM, Meyer JC, Anderson E, Patel RH, Gomes PJ, Reilly E, Vantipalli S, Cheung MW, Goldstein MH.   +10 more
europepmc   +1 more source

Efficacy and safety of switching to bilastine, an H1-antihistamine, in patients with refractory chronic spontaneous urticaria (H1-SWITCH): a multicenter, open-label, randomized, parallel-group comparative study. [PDF]

Front Immunol
Fukunaga A, Kakei Y, Murakami S, Kan Y, Masuda K, Jinnin M, Washio K, Amano H, Nagano T, Yamamoto A, Otsuka T, Takahagi S, Takenaka M, Ishiguro N, Hayama K, Inomata N, Nakagawa Y, Sugiyama A, Hide M.   +18 more
europepmc   +1 more source

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Bepotastine Besilate for the Treatment of Perennial Allergic Rhinitis

Expert Opinion on Pharmacotherapy, 2018
Introduction: Bepotastine besilate (BB) is a second-generation H1-antihistamine that, as an ophthalmic solution, is approved in the United States by the Food and Drug Administration (FDA) for the treatment of allergic conjunctivitis.
Alexei Gonzalez-Estrada, Ismael Carrillo-Martín, Vés Dimov   +2 more
exaly   +4 more sources

Improved Synthesis of Bepotastine Besilate

Organic Preparations and Procedures International, 2021
Bepotastine besilate (1, Figure 1, synonymous with bepotastine besylate), is a non-sedative highly selective histamine receptor antagonist, which has a stabilizing effect on mast cells.
C. Han, Y.-Y. Xia, Q. Sun, Qiao-Gen Zou
semanticscholar   +2 more sources

Characterization of photodegradation products of bepotastine besilate and in silico evaluation of their ADMET properties.

Journal of Pharmacy and Science, 2020
Bepotastine (BPT) is a H1-receptor antagonist. It is used as a besilate salt in ophthalmic solution for allergic conjunctivitis, and orally for the treatment of allergic rhinitis and utricaria/pruritus.
D. Singh, A. Sahu, A. Wani, P. Bharatam, A. Chakraborti, S. Giri, Saranjit Singh   +6 more
semanticscholar   +2 more sources

Double-Blind Placebo-Controlled Study of Bepotastine Besilate in Pediatric Patients With Perennial Allergic Rhinitis

Expert Opinion on Pharmacotherapy, 2015
Although second-generation antihistamines, such as bepotastine besilate, are recommended as a first-line treatment option for adult perennial allergic rhinitis (PAR), few non-sedating second-generation antihistamines are safe for children.A double-blind, placebo-controlled, comparative study of 473 pediatric PAR patients (7 - 15 years old) to determine
Kimihiro Okubo
exaly   +4 more sources

Non-Clinical Pharmacology, Pharmacokinetics, and Safety Findings for the Antihistamine Bepotastine Besilate

Current Medical Research and Opinion, 2010
The purpose of this review is to examine published non-clinical literature on the antihistamine bepotastine besilate, including pharmacokinetic and pharmacologic properties.Standard literature searches using diverse databases were used to find articles on bepotastine besilate published between 1997 and 2009.
Sharon M Klier
exaly   +4 more sources

Bepotastine besilate downregulates the expression of nerve elongation factors in normal human epidermal keratinocytes.

Journal of Dermatological Science, 2018
Y. Kamata, Azumi Sakaguchi, Y. Umehara, Y. Suga, H. Ogawa, M. Tominaga, K. Takamori   +6 more
semanticscholar   +4 more sources

Comparative Efficacy and Safety of Topical Bepotastine Besilate 1.5% Versus Sodium Cromoglycate 4% in Chronic Allergic Conjunctivitis: A Prospective Study.

Journal of Ocular Pharmacology and Therapeutics
Purpose: To compare the efficacy, safety, and patient satisfaction of bepotastine besilate 1.5% versus sodium cromoglycate 4% eye drops in the management of chronic allergic conjunctivitis.
Mayank Jhanwar, Sumit Goyal
exaly   +2 more sources

Identification, Characterization and HPLC Quantification of Process-Related Impurities in Bepotastine Besilate Bulk Drug

Drug Research, 2019
Bepotastine besilate (here after referred to as BTST), chemically known as ({d(S)4[4[(4chlorophenyl) (2pyridyl) methoxy] piperidino} butyric acid monobenzene sulphonate), is a second-generation antihistamine drug. To the best of our knowledge, no studies
Chao-Weiguan-Li-Ren-Yang-Yuan-Qing Zhang, C. Han, Lili Sun, Jinlong Yu, Qiao-Gen Zou   +4 more
semanticscholar   +3 more sources