Prediction of complex human traits using the genomic best linear unbiased predictor. [PDF]
Despite important advances from Genome Wide Association Studies (GWAS), for most complex human traits and diseases, a sizable proportion of genetic variance remains unexplained and prediction accuracy (PA) is usually low. Evidence suggests that PA can be
Gustavo de Los Campos +4 more
doaj +6 more sources
Approximation of reliabilities for random-regression single-step genomic best linear unbiased predictor models [PDF]
Random-regression models (RRM) are used in national genetic evaluations for longitudinal traits. The outputs of RRM are an index based on random-regression coefficients and its reliability.
M. Bermann +6 more
doaj +4 more sources
Breeding value reliabilities for multiple-trait single-step genomic best linear unbiased predictor
: Approximate multistep methods to calculate reliabilities for estimated breeding values in large genetic evaluations were developed for single-trait (ST-R2A) and multitrait (MT-R2A) single-step genomic BLUP (ssGBLUP) models.
Hafedh Ben Zaabza +5 more
doaj +5 more sources
Multi-Trait, Multi-Environment Genomic Prediction of Durum Wheat With Genomic Best Linear Unbiased Predictor and Deep Learning Methods [PDF]
Although durum wheat (Triticum turgidum var. durum Desf.) is a minor cereal crop representing just 5–7% of the world’s total wheat crop, it is a staple food in Mediterranean countries, where it is used to produce pasta, couscous, bulgur and bread.
Osval A. Montesinos-López +6 more
doaj +2 more sources
Multivariate best linear unbiased predictor as a tool to improve multi-trait selection in sugarcane [PDF]
: The objective of this work was to evaluate the use of the multivariate best linear unbiased predictor (BLUP) method for multi-trait selection, to estimate the genetic parameters in sugarcane (Saccharum officinarum) genotypes. The experiment was carried
Ivan Ricardo Carvalho +9 more
doaj +5 more sources
Efficient approximation of reliabilities for single-step genomic best linear unbiased predictor models with the Algorithm for Proven and Young. [PDF]
AbstractThe objectives of this study were to develop an efficient algorithm for calculating prediction error variances (PEVs) for genomic best linear unbiased prediction (GBLUP) models using the Algorithm for Proven and Young (APY), extend it to single-step GBLUP (ssGBLUP), and apply this algorithm for approximating the theoretical reliabilities for ...
Bermann M, Lourenco D, Misztal I.
europepmc +4 more sources
Comparing algorithms to approximate accuracies for single-step genomic best linear unbiased predictor. [PDF]
Abstract The exact accuracy of estimated breeding values can be calculated based on the prediction error variances obtained from the diagonal of the inverse of the left-hand side (LHS) of the mixed model equations (MME). However, inverting the LHS is not computationally feasible for large datasets, especially if genomic information is ...
Ramos P +7 more
europepmc +3 more sources
Ensemble Learning of Convolutional Neural Network, Support Vector Machine, and Best Linear Unbiased Predictor for Brain Age Prediction: ARAMIS Contribution to the Predictive Analytics Competition 2019 Challenge [PDF]
We ranked third in the Predictive Analytics Competition (PAC) 2019 challenge by achieving a mean absolute error (MAE) of 3.33 years in predicting age from T1-weighted MRI brain images.
Baptiste Couvy-Duchesne +51 more
doaj +2 more sources
122 Comparison of Algorithms for Approximation of Accuracies for Single-Step Genomic Best Linear Unbiased Predictor Models [PDF]
Abstract The theoretical accuracy of breeding values can be calculated based on the prediction error variances obtained from the diagonal of the inverse of the left-hand side of the mixed model equations. However, inverting the coefficient matrix is not computationally feasible for an extensive system of equations, especially if genomic ...
Pedro Vital Brasil Ramos +5 more
europepmc +2 more sources
Weighted single-step genomic best linear unbiased predictor enhances the genomic prediction accuracy for milk citrate predicted by milk mid-infrared spectra of Holstein cows in early lactation [PDF]
Previous studies have shown that milk citrate predicted by milk mid-infrared (MIR) spectra is strongly affected by a few genomic regions. This study aimed to explore the effect of weighted single-step GBLUP on the accuracy of genomic prediction (GP) for ...
Y. Chen +3 more
doaj +2 more sources

