Results 71 to 80 of about 416,993 (285)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Best Proximity Point Result in Modular Spaces with the Fatou Property

Abstract and Applied Analysis, 2013
Consider a nonself-mapping , where is a pair of nonempty subsets of a modular space . A best proximity point of is a point satisfying the condition: .
Mohamed Jleli, Erdal Karapınar, Bessem Samet   +2 more
doaj   +1 more source

Non-convex proximal pair and relatively nonexpansive maps with respect to orbits

Journal of Inequalities and Applications, 2021
Every non-convex pair ( C , D ) $(C, D)$ may not have proximal normal structure even in a Hilbert space. In this article, we use cyclic relatively nonexpansive maps with respect to orbits to show the presence of best proximity points in C ∪ D $C\cup D$ ,
Laishram Shanjit, Yumnam Rohen
doaj   +1 more source

Recurrent oligomers in proteins - an optimal scheme reconciling accurate and concise backbone representations in automated folding and design studies

, 2000
A novel scheme is introduced to capture the spatial correlations of consecutive amino acids in naturally occurring proteins. This knowledge-based strategy is able to carry out optimally automated subdivisions of protein fragments into classes of ...
Maritan, Amos, Micheletti, Cristian, Seno, Flavio   +2 more
core   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Best proximity point theorems for cyclic p-contractions with some consequences and applications

Nonlinear Analysis, 2021
In this paper, we introduce the concept of cyclic p-contraction pair for single-valued mappings. Then we present some best proximity point results for such mappings defined on proximally complete pair of subsets of a metric space.
Mustafa Aslantas, Hakan Sahin, Ishak Altun   +2 more
doaj   +1 more source

Examining collusion and voting biases between countries during the Eurovision song contest since 1957

, 2017
The Eurovision Song Contest (ESC) is an annual event which attracts millions of viewers. It is an interesting activity to examine since the participants of the competition represent a particular country's musical performance that will be awarded a set of
Hopkins, Alexander D., Mantzaris, Alexander V., Rein, Samuel R.   +2 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Cyclic (noncyclic) phi-condensing operator and its application to a system of differential equations

Nonlinear Analysis, 2019
We establish a best proximity pair theorem for noncyclic φ-condensing operators in strictly convex Banach spaces by using a measure of noncompactness. We also obtain a counterpart result for cyclic φ-condensing operators in Banach spaces to guarantee the
Moosa Moosa Gabeleh, Seithuti Philemon Moshokoa, Calogero Vetro   +2 more
doaj   +3 more sources

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source