Results 61 to 70 of about 916,486 (287)

Faint AGN and the Ionizing Background [PDF]

, 2002
We determine the evolution of the faint, high-redshift, optical luminosity function (LF) of AGN implied by several observationally-motivated models of the ionizing background.
Boyle B. J., Cavaliere A., Chokshi A., Comastri A., Cooke A. J., Cristiani S., Dickinson M., Efstathiou G., Ferguson H. C., Fernandez-Soto A., Haehnelt M. G., Heckman T. M., James S. Bullock, Kormendy J., Lynden-Bell D., Michael Schirber, Miyaji T., Richstone D., Soltan A., Wadsley J., Zeldovich Ya. B.   +20 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tripled Fixed Points and Tripled Best Proximity Points in Modular Function Spaces

AppliedMath
We establish a modular-space framework for the study of tripled fixed points and tripled best proximity points. Under suitable assumptions on the underlying modular (convexity, the Δ2 property, uniform continuity, and uniform convexity-type properties ...
Aynur Ali, Miroslav Hristov, Atanas Ilchev, Diana Nedelcheva, Boyan Zlatanov   +4 more
doaj   +1 more source

Downs, Stokes and the Dynamics of Electoral Choice [PDF]

, 2011
A six-wave 2005–09 national panel survey conducted in conjunction with the British Election Study provided data for an investigation of sources of stability and change in voters’ party preferences.
Bara, Budge, Burnham, Campbell, Charemza, Clarke, David Sanders, Downs, Enders, Enelow, Fiorina, Gigerenzer, Harold D. Clarke, Lupia, Marianne C. Stewart, Paul Whiteley, Popkin, Roderick Kiewiet, Sanders, Scott Long, Stokes, Tomz, Wlezien, Wooldridge   +23 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Offline reconstruction of missing vehicle trajectory data from 3D LIDAR

, 2017
LIDAR has become an important part of many autonomous vehicles with its advantages on distance measurement and obstacle detection. LIDAR produces point clouds which have important information about surrounding environment.
Cetin, Mecit, Nezafat, Reza Vatani, Sazara, Cem   +2 more
core   +1 more source

On Best Proximity Point Theorems without Ordering

Abstract and Applied Analysis, 2014
Recently, Basha (2013) addressed a problem that amalgamates approximation and optimization in the setting of a partially ordered set that is endowed with a metric. He assumed that ifAandBare nonvoid subsets of a partially ordered set that is equipped with a metric andSis a non-self-mapping fromAtoB, then the mappingShas an optimal approximate solution,
Ali Farajzadeh, Somyot Plubtieng, Kasamsuk Ungchittrakool   +2 more
openaire   +4 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Best proximity points of p-cyclic orbital Meir–Keeler contraction maps

Nonlinear Analysis, 2016
Let (X,d) be a metric space and A1, A2, ..., Ap be nonempty subsets of X. We introduce a self map T on X, called p-cyclic orbital contraction map on the union of A1, A2, ..., Ap and obtain a unique best proximity point of T.
Saravanan Karpagam, Boyan Zlatanov
doaj   +1 more source