Results 21 to 30 of about 93,633 (196)

The role of plasma concentrations and drug characteristics of beta‐blockers in fall risk of older persons

Pharmacology Research & Perspectives, 2023
Beta‐blocker usage is inconsistently associated with increased fall risk in the literature. However, due to age‐related changes and interindividual heterogeneity in pharmacokinetics and dynamics, it is difficult to predict which older adults are more at ...
K. J. Ploegmakers, E. P. vanPoelgeest, L. J. Seppala, S. C. vanDijk, L. C. P. G. M. deGroot, S. Oliai Araghi, N. M. vanSchoor, B. Stricker, K. M. A. Swart, A. G. Uitterlinden, R. A. A. Mathôt, N. van derVelde   +11 more
doaj   +1 more source

The association between beta-blocker use and chronic obstructive pulmonary disease risk, severity, and exacerbation

Medical Journal of Babylon, 2021
Background: There is controversy about the role of beta-blockers in the number of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Hemin Khalid Saber
doaj   +1 more source

Efficacy and Tolerability of Travoprost 0.004%/Timolol 0.5% Fixed-Dose Combination for the Treatment of Primary Open-Angle Glaucoma or Ocular Hypertension Inadequately Controlled with Beta-Blocker Monotherapy

Journal of Ophthalmology, 2017
Objective. To evaluate the efficacy and tolerability of travoprost 0.004%/timolol 0.5% fixed-dose combination (TTFC) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) inadequately controlled on beta-blocker monotherapy. Methods.
Simon Fabian Lerner, Ki Ho Park, Douglas A. Hubatsch, Valeriy Erichev, Jose A. Paczka, Timothy V. Roberts   +5 more
doaj   +1 more source

Evaluation of Perioperative Beta-Blockers and Factors Associated with Postoperative Atrial Fibrillation in Cardiac Surgery: A Single Center Experience

Reviews in Cardiovascular Medicine, 2023
Background: Postoperative atrial fibrillation (AF) has a complex etiology, and beta-blockers are commonly recommended for its pharmacological prevention.
Alexandra Puscas, Marius M. Harpa, Klara Brinzaniuc, Hussam Al-Hussein, Hamida Al-Hussein, Cosmin Banceu, Carmen Opris, Claudiu Ghiragosian, Sanziana Flamind, Robert Balan, Septimiu Voidazan, Horatiu Suciu   +11 more
doaj   +1 more source

THE CHOICE OF DRUG FROM THE STANDPOINT OF EVIDENCE-BASED MEDICINE: CASE STUDY OF BETA-BLOCKERS

Рациональная фармакотерапия в кардиологии, 2016
Basic principles of beta-blockers choice strategy are presented. Attention is focused on the facts concerning the evidence base for effects of various beta-blockers on the outcomes of cardiovascular diseases.
S. Yu. Martsevich, N. P. Kutishenko, Yu. V. Lukina   +2 more
doaj   +1 more source

Preoperative beta-blocker in ventricular dysfunction patients: need a more granular quality metric

BMC Cardiovascular Disorders, 2021
Background The use of preoperative beta-blockers has been accepted as a quality standard for patients undergoing coronary artery bypass graft (CABG) surgery.
Hanwei Tang, Kai Chen, Jianfeng Hou, Xiaohong Huang, Sheng Liu, Shengshou Hu   +5 more
doaj   +1 more source

Beta-Blocker-Related Atrioventricular Conduction Disorders—A Single Tertiary Referral Center Experience

Medicina, 2022
Background and Objectives: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions.
Dragoș Traian Marius Marcu, Cristina Andreea Adam, Dan-Mihai Dorobanțu, Delia Lidia Șalaru, Radu Andy Sascău, Mircea Ovanez Balasanian, Liviu Macovei, Cătălina Arsenescu-Georgescu, Cristian Stătescu   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Use of beta-blockers and risk of serious upper gastrointestinal bleeding: a population-based case-control study

Therapeutic Advances in Gastroenterology, 2017
Background: Some studies indicate a reduced risk of serious upper gastrointestinal bleeding (UGIB) for users of beta-blockers, but the association remains to be confirmed in larger studies and characterized with respect to differences among beta-blockers.
Mette Reilev, Per Damkier, Lotte Rasmussen, Morten Olesen, Martin Thomsen Ernst, Rikke Mie Rishøj, Morten Rix Hansen, Anne Broe, Alexander Steenberg Dastrup, Maja Hellfritzsch, Sidsel Arnspang, Anton Pottegård, Jesper Hallas   +12 more
doaj   +1 more source