Results 31 to 40 of about 692,791 (244)

Evaluation of Perioperative Beta-Blockers and Factors Associated with Postoperative Atrial Fibrillation in Cardiac Surgery: A Single Center Experience

Reviews in Cardiovascular Medicine, 2023
Background: Postoperative atrial fibrillation (AF) has a complex etiology, and beta-blockers are commonly recommended for its pharmacological prevention.
Alexandra Puscas, Marius M. Harpa, Klara Brinzaniuc, Hussam Al-Hussein, Hamida Al-Hussein, Cosmin Banceu, Carmen Opris, Claudiu Ghiragosian, Sanziana Flamind, Robert Balan, Septimiu Voidazan, Horatiu Suciu   +11 more
doaj   +1 more source

Preoperative beta-blocker in ventricular dysfunction patients: need a more granular quality metric

BMC Cardiovascular Disorders, 2021
Background The use of preoperative beta-blockers has been accepted as a quality standard for patients undergoing coronary artery bypass graft (CABG) surgery.
Hanwei Tang, Kai Chen, Jianfeng Hou, Xiaohong Huang, Sheng Liu, Shengshou Hu   +5 more
doaj   +1 more source

Beta-blocker-induced diabetes risk vs. the binding affinity for incretin receptors and other class B GPCRs.

, 2019
GUT-DOCK (Autodock VINA) results for selected beta-blockers (A). T2DM-related ranks were assigned according to [58, 61–66] and average GUT-DOCK results (see Table 3): 0 –compound 15, 1 –carvedilol, 2 –nebivolol, 3 –labetalol, 4—atenolol, 5 –metoprolol (1
Pawel Pasznik (384253), Dorota Latek (95762), Ewelina Rutkowska (2620405), Judyta Cielecka-Piontek (715035), Szymon Niewieczerzal (4017512)   +4 more
core   +1 more source

Beta-Blocker-Related Atrioventricular Conduction Disorders—A Single Tertiary Referral Center Experience

Medicina, 2022
Background and Objectives: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions.
Dragoș Traian Marius Marcu, Cristina Andreea Adam, Dan-Mihai Dorobanțu, Delia Lidia Șalaru, Radu Andy Sascău, Mircea Ovanez Balasanian, Liviu Macovei, Cătălina Arsenescu-Georgescu, Cristian Stătescu   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Use of beta-blockers and risk of serious upper gastrointestinal bleeding: a population-based case-control study

Therapeutic Advances in Gastroenterology, 2017
Background: Some studies indicate a reduced risk of serious upper gastrointestinal bleeding (UGIB) for users of beta-blockers, but the association remains to be confirmed in larger studies and characterized with respect to differences among beta-blockers.
Mette Reilev, Per Damkier, Lotte Rasmussen, Morten Olesen, Martin Thomsen Ernst, Rikke Mie Rishøj, Morten Rix Hansen, Anne Broe, Alexander Steenberg Dastrup, Maja Hellfritzsch, Sidsel Arnspang, Anton Pottegård, Jesper Hallas   +12 more
doaj   +1 more source

GAMBARAN PERESEPAN OBAT BETA BLOCKER PADA PASIEN GAGAL JANTUNG SISTOLIK YANG DIRAWAT JALAN DI RSUP DR. KARIADI SEMARANG

Jurnal Kedokteran Diponegoro, 2018
Latar Belakang: Gagal jantung sistolik merupakan kegagalan jantung untuk memberikan suplai darah dalam memenuhi kebutuhan metabolisme jaringan dengan hipertrofi dinding ventrikel yang memiliki output terbatas karena ejeksi yang terganggu selama sistol ...
Monica Destiani, Ilham Uddin, Pipin Ardhianto   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Randomized Evaluation of Beta Blocker and ACE-Inhibitor/Angiotensin Receptor Blocker Treatment for Post Infarct Angina in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries : A MINOCA-BAT Sub Study Rationale and Design

, 2021
Introduction: Myocardial infarction with non-obstructive coronary arteries (MINOCA) occurs in ~10% of all patients with acute myocardial infarction (AMI), with an over-representation amongst women.
Tavella, Rosanna,, Beltrame, John F, Rajwani, Adil,, Mooney, John, Singh, Kuljit, Nordenskjöld, Anna M., Arstall, Margaret, Worthley, Matthew, Nordenskjöld, Anna M.,, Singh, Kuljit,, Zeitz, Christopher,, Tavella, Rosanna, Arstall, Margaret,, Beltrame, John F., Nordenskjold, Anna M, Neil, Christopher,, Neil, Christopher, Lindahl, Bertil, Pasupathy, Sivabaskari,, Rajwani, Adil, Turner, Stuart,, Lindahl, Bertil,, Zeitz, Christopher, Mooney, John,, Pasupathy, Sivabaskari, Worthley, Matthew,, Beltrame, John F.,, Turner, Stuart   +27 more
core   +1 more source